Effect of Stroke Volume Variation Guided Fluid Therapy on the Blood Loss and Postoperative Outcomes in Radical Cystectomy
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Bladder Cancer
- Sponsor
- Asan Medical Center
- Enrollment
- 64
- Locations
- 1
- Primary Endpoint
- Intraoperative blood loss
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The purpose of this study is to investigate the effect of stroke volume variation (SVV) guided fluid therapy on the blood loss and postoperative outcomes in radical cystectomy.
Detailed Description
The purpose of this study is to investigate the effect of stroke volume variation(SVV) guided fluid therapy on the blood loss and postoperative outcomes in radical cystectomy. Patients were randomized to fluid management to maintain \<10% SVV (group A), or to undergo fluid management during radical cystectomy to maintain SVV 10-20% (group B). Intraoperative blood loss and hemodynamic parameters, perioperative laboratory data, and postoperative complications were compared between two groups.
Investigators
Young-Kug Kim
professor
Asan Medical Center
Eligibility Criteria
Inclusion Criteria
- •Bladder cancer patients who received radical cystectomy
- •Patients with American Society of Anesthesiologists physical status scale classification 1, 2
- •Patients who agree with written informed consent
Exclusion Criteria
- •Patients with history of arrhythmia, heart failure patients
- •Patients with history of renal failure patients
- •Patients with history of abdominal surgery
- •Patients who received emergency operation
- •Patients who do not agree with study
Outcomes
Primary Outcomes
Intraoperative blood loss
Time Frame: During operation
Secondary Outcomes
- Postoperative complications (cardiovascular complications, gastrointestinal complications, pulmonary complications, renal complications, infection, death)(During 30 days after operation)
- Length of hospital stay/ICU stay(participants will be followed for the duration of hospital stay, an expected average of 30 days)