Effect of Stroke Volume Variation Guided Fluid Therapy on the Blood Loss and Postoperative Outcomes in Radical Cystectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 64
- 试验地点
- 2
- 主要终点
- Intraoperative blood loss
研究概览
简要总结
The purpose of this study is to investigate the effect of stroke volume variation (SVV) guided fluid therapy on the blood loss and postoperative outcomes in radical cystectomy.
详细描述
The purpose of this study is to investigate the effect of stroke volume variation(SVV) guided fluid therapy on the blood loss and postoperative outcomes in radical cystectomy. Patients were randomized to fluid management to maintain <10% SVV (group A), or to undergo fluid management during radical cystectomy to maintain SVV 10-20% (group B). Intraoperative blood loss and hemodynamic parameters, perioperative laboratory data, and postoperative complications were compared between two groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Bladder cancer patients who received radical cystectomy
- •Patients with American Society of Anesthesiologists physical status scale classification 1, 2
- •Patients who agree with written informed consent
排除标准
- •Patients with history of arrhythmia, heart failure patients
- •Patients with history of renal failure patients
- •Patients with history of abdominal surgery
- •Patients who received emergency operation
- •Patients who do not agree with study
结局指标
主要结局
Intraoperative blood loss
时间窗: During operation
次要结局
- Postoperative complications (cardiovascular complications, gastrointestinal complications, pulmonary complications, renal complications, infection, death)(During 30 days after operation)
- Length of hospital stay/ICU stay(participants will be followed for the duration of hospital stay, an expected average of 30 days)
研究者
Young-Kug Kim
professor
Asan Medical Center