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Lung Recruitment Maneuver for Predicting Fluid Responsiveness in Children

Not Applicable
Completed
Conditions
Hypovolemia
Interventions
Diagnostic Test: lung recruitment maneuver
Registration Number
NCT03184961
Lead Sponsor
Seoul National University Hospital
Brief Summary

Lung recruitment maneuver induces a decrease in stroke volume, which is more pronounced in hypovolemic patients. The authors hypothesized that the changes of dynamic variables through lung recruitment maneuver could predict preload responsiveness in pediatric patients with lung protective ventilation

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • pediatric patients undergoing general anesthesia under 6 years old
Exclusion Criteria
  • arrhythmia
  • <30%, ejection fraction
  • lung disease

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
lung recruitment maneuverlung recruitment maneuverHeart rate, mean arterial pressure, stroke volume, pulse pressure variations, pleth variability index, and photoplethysmographic waveform were recorded before lung recruitment maneuver (application of continuous positive airway pressure of 25 cm H2O for 20 s), during lung recruitment maneuver when stroke volume reached its minimal value. Cardiac index measured before and after volume expansion (10ml/kg saline, 0.9%, infused during 10 min). Patients were considered as responders to fluid administration if cardiac index increased greater than or equal to 15%.
Primary Outcome Measures
NameTimeMethod
photoplethysmographic waveformchange from baseline photoplethysmographic waveform after lung recruitment maneuver within 30 seconds
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Seoul National University Hospital

🇰🇷

Seoul, Korea, Republic of

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