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Clinical Trials/NCT01780415
NCT01780415
Unknown
Not Applicable

Genomic DNA in Human Blastocoele Fluid

Cervesi Hospital, Cattolica, Italy1 site in 1 country35 target enrollmentJanuary 2013
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ConditionsChromosomal AneuploidiesSingle Gene Desease

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chromosomal Aneuploidies
Sponsor
Cervesi Hospital, Cattolica, Italy
Enrollment
35
Locations
1
Primary Endpoint
Number of samples with DNA in blastocoele Fluid
Last Updated
5 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The objective will focus on the characterization of DNA fragments present in Blastocoele fluid, and the evaluation of these fragments as potential target for Preimplantation Genetic Diagnosis. To reach this goal, real-time PCR, Whole Genome Amplification techniques and -subsequently- Next Generation Sequencing and aCGH approaches will be used.

Registry
clinicaltrials.gov
Start Date
January 2013
End Date
January 2022
Last Updated
5 years ago
Study Type
Observational
Sex
Female

Investigators

Sponsor
Cervesi Hospital, Cattolica, Italy
Responsible Party
Principal Investigator
Principal Investigator

Palini Simone

Senior Clinical Embryologist

Cervesi Hospital, Cattolica, Italy

Eligibility Criteria

Inclusion Criteria

  • •IVF patient with supernumerary embryos to vitrify at blastocyst stage

Exclusion Criteria

  • •IVF patient without blastocyst formation

Outcomes

Primary Outcomes

Number of samples with DNA in blastocoele Fluid

Time Frame: 6 month

the presence of DNA will be evaluated through rtPCR

Secondary Outcomes

  • Number of euploid samples(8 months)

Study Sites (1)

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