TO assess the effect of vibration and low level laser therapy on the amount of IL1- Beta, IL-8 andorthodontic tooth movement
Not Applicable
- Registration Number
- CTRI/2022/08/044842
- Lead Sponsor
- Dr Aastha Purohit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Healthy Individuals with no systemic illness requiring maxillary first premolar extraction.
Good oral
hygiene and periodontal health.
No developmental anomaly.
No history of previous orthodontic treatment.
Exclusion Criteria
History of trauma.
Patients with systemic illnesses
Taking medications that interfere with orthodontic tooth movement
Patients with parafunctional habits
Severely periodontally compromised.
Periapical inflammation of cysts/ tumors.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The efficacy of high frequency vibrations <br/ ><br>combined with low level laser therapy is <br/ ><br>expected to be higher than low level laser <br/ ><br>therapy which is higher than control group which <br/ ><br>is not receiving any laser or vibration therapy on <br/ ><br>the levels of Interleukin-1 beta and Interleukin-8 <br/ ><br>in Gingival Crevicular Fluid.Timepoint: 3 months
- Secondary Outcome Measures
Name Time Method Group receiving high frequency vibrations <br/ ><br>combined with low level laser therapy is <br/ ><br>expected to increase orthodontic tooth <br/ ><br>movement most followed by group receiving only <br/ ><br>low level laser therapy followed by control group <br/ ><br>which is not receiving any laser or vibration <br/ ><br>therapyTimepoint: 3 months