TO assess the effect of vibration and low level laser therapy on the amount of IL1- Beta, IL-8 and orthodontic tooth movement
Not Applicable
- Conditions
- Health Condition 1: K089- Disorder of teeth and supporting structures, unspecified
- Registration Number
- CTRI/2022/08/044816
- Lead Sponsor
- Dr Aastha Purohit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients requiring maxillary first premolar extraction.
Good oral hygiene and periodontal health.
Patients aged 14 years and above.
No developmental anomaly of dento-alveolar structures.
No history of previous orthodontic treatment.
Exclusion Criteria
History of trauma.
Patients with systemic illnesses
Taking medications that interfere with orthodontic tooth movement
Patients with parafunctional habits
Severely periodontally compromised.
Periapical inflammation of cysts/ tumors.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The efficacy of high frequency vibrations combined with low level laser therapy is expected to be higher than low level laser therapy which is higher than control group which is not receiving any laser or vibration therapy on the levels of Interleukin-1 beta and Interleukin-8 in Gingival Crevicular Fluid.Timepoint: Pre sample of GCF will be compared with GCF sample 3 months post retraction
- Secondary Outcome Measures
Name Time Method Group receiving high frequency vibrations combined with low level laser therapy is expected to increase orthodontic tooth movement most followed by group receiving only low level laser therapy followed by control group which is not receiving any laser or vibration therapy.Timepoint: Amount of tooth movement will be checked after 3 months of retraction.