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The anabolic response following ingestion of a plant-based protein product in vivo in healthy young me

Recruiting
Conditions
Muscle hypertrophy
10037008
gezonde voeding
muscle growth
10028302
Registration Number
NL-OMON45741
Lead Sponsor
niversiteit Maastricht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
34
Inclusion Criteria

* Males
* Aged between 18 - 35 years
* Healthy, recreationally active (max 3 days per week performing activities)
* BMI 18.5 * 27.5 kg/m2

Exclusion Criteria

* Females
* Diagnosed Diabetes
* Wheat allergy
* Celiac disease
* Smoking
* Diagnosed metabolic or intestinal disorders
* A history of neuromuscular problems
* Any medications known to (or may) affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).
* Participation in structured resistance exercise program

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>The main study endpoint is the fractional synthetic rate (FSR) of muscle<br /><br>protein synthesis<br /><br>In order to determine the FSR, the following parameters will be measured:<br /><br>* Muscle protein-bound L-[ring-13C6]-phenylalanine enrichments (expressed as<br /><br>MPE)<br /><br>* Muscle tissue-free L-[ring-13C6]-phenylalanine enrichments (expressed as MPE)<br /><br>* Plasma L-[ring-13C6]-phenylalanine enrichments (expressed as MPE) </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Amino acid concentrations, glucose and insulin concentrations<br /><br>GI-complaints and palatability after ingestion of the meals (VAS questionnaire)</p><br>
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