The anabolic response following ingestion of a plant-based protein product in vivo in healthy young me
- Conditions
- Muscle hypertrophy10037008gezonde voedingmuscle growth10028302
- Registration Number
- NL-OMON45741
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 34
* Males
* Aged between 18 - 35 years
* Healthy, recreationally active (max 3 days per week performing activities)
* BMI 18.5 * 27.5 kg/m2
* Females
* Diagnosed Diabetes
* Wheat allergy
* Celiac disease
* Smoking
* Diagnosed metabolic or intestinal disorders
* A history of neuromuscular problems
* Any medications known to (or may) affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescription strength acne medications).
* Participation in structured resistance exercise program
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study endpoint is the fractional synthetic rate (FSR) of muscle<br /><br>protein synthesis<br /><br>In order to determine the FSR, the following parameters will be measured:<br /><br>* Muscle protein-bound L-[ring-13C6]-phenylalanine enrichments (expressed as<br /><br>MPE)<br /><br>* Muscle tissue-free L-[ring-13C6]-phenylalanine enrichments (expressed as MPE)<br /><br>* Plasma L-[ring-13C6]-phenylalanine enrichments (expressed as MPE) </p><br>
- Secondary Outcome Measures
Name Time Method <p>Amino acid concentrations, glucose and insulin concentrations<br /><br>GI-complaints and palatability after ingestion of the meals (VAS questionnaire)</p><br>