NCT02540005已完成不适用
Coagulation Disorders After Aneurysmatic Subarachnoid Haemorrhage
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- ROTEM analysis: MCF (mm) by EXTEM activators
研究概览
简要总结
The main purpose of this study is to analyse the on-going coagulation process after aSAH. For investigation the investigators use the rotational thromboelastometry (ROTEM) which is a point-of-care test using a variety of activators to provide a targeted and a dynamic analysis of coagulation cascade. This is a prospective, observational clinical study done in 16 aSAH patients treated in Tampere University Hospital intensive care unit and 16 control patients (elective craniotomy due to non-ruptured intracranial aneurysm.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 18 years
- •Acute subarachnoid haemorrhage (confirmed by computed tomography, CT, or cerebrospinal fluid erythrocyte count over 1000 x 106/l) AND confirmed origin either with computed angiography (CTA) or digital subtraction angiography (DSA)
- •Onset of symptoms ≤ 12 hours
- •Expected to stay 72 hours in the ICU
排除标准
- •Pregnancy
- •Any long-term anticoagulant medication, except for low-dose aspirin (<150 mg/day)
- •Known active cancer
结局指标
主要结局
ROTEM analysis: MCF (mm) by EXTEM activators
时间窗: 12 hours
次要结局
未报告次要终点
研究者
Annukka Vahtera
MD
Tampere University Hospital
研究点 (1)
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