The effect of nutritional supplementation as adjunct to exercise training on resting and exercise-induced oxidative stress, muscle function and exercise capacity in severe COPD patients.

AMWJ Schols, Prof Director NUTRIMUniversity MaastrichtPostbus 6166200 MD Maastrichtthe Netherlands0 sites30 target enrollmentTBD

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: COPD, supplementation, antioxidants, rehabilitationCOPD, supplementatie, antioxidatnen, revalidatie
Sponsor: AMWJ Schols, Prof Director NUTRIMUniversity MaastrichtPostbus 6166200 MD Maastrichtthe Netherlands
Enrollment: 30
Status: Not yet recruiting
Last Updated: 2 years ago

No summary available.

Registry

who.int

Start Date

TBD

End Date

TBD

Last Updated

2 years ago

Study Type

Interventional

Sponsor

AMWJ Schols, Prof Director NUTRIMUniversity MaastrichtPostbus 6166200 MD Maastrichtthe Netherlands

•1\. Diagnosis of COPD according to the American Thoracic Society (ATS) GOLD guidelines (FEV1 \< 60% predicted and FEV1/FVC \< 70% and \< 10% predicted improvement in FEV1 after b2\-agonist inhalation (14, 15\));
•2\. Both male and female, age\-range from 40 to 75 years;
•3\. No respiratory tract infection or exacerbation of the disease for at least 4 weeks before the study;
•4\. Capable to provide informed consent;
•5\. Presence of other chronic diseases is allowed in case the clinical status is stable for at least 4 weeks before the study.

•1\. Inability to perform the incremental cycle ergometer test;
•2\. Chronic use of antioxidants or vitamin supplements;
•3\. Investigator's uncertainty about the willingness or ability of the patient to comply with the protocol requirements;
•4\. Participation in any other studies involving investigational or marketed products concomitantly or within two weeks prior to entry into the study;
•5\. Specific allergy or intolerance.