Acute Effect of Passive Joint Mobilization on Joint Motion And Pain Perception in Non-Specific Neck Pain
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 53
- Locations
- 2
- Primary Endpoint
- Pain Pressure Threshold
Study Overview
Brief Summary
Aim of present study is investigating the acute effects of passive joint mobilization on pain perception and range of motion. Study protocol includes passive joint mobilization application to study group with neck pain and blood sample collection of study and healthy control group.
Detailed Description
Our purpose of planning this study is to examine the acute effect of passive joint mobilization application on pain perception and range of motion in women with non-specific neck pain.
The hypotheses we will test for this purpose;
H1- Passive joint mobilization application increases the range of motion of the cervical joint in women with non-specific neck pain.
H2- Passive joint mobilization application increases the pressure pain threshold in women with non-specific neck pain.
H3- Passive joint mobilization increases serum Orexin A and Neurotensin levels in women with non-specific neck pain.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 24 Years to 45 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •For Intervention Group;
- •Having neck pain lasting more than 30 days and being diagnosed with non-specific neck pain
- •Having obtained 14/50 points and above in Neck Disability Index
- •Expressing neck pain at least 34/100 points and above on a Visual Analog Scale
- •Being 20-45 years old and female
- •For Healthy Control Group;
- •Healthy volunteers without a chronic illness and musculoskeletal pain
Exclusion Criteria
- •Congenital anomalies
- •Previously diagnosed orthopedic diseases related to the spine
- •Pregnancy and having just given birth
- •Within the last 3 months; use of corticosteroids, cytotoxic drugs, or immunosuppressants
- •Liver or kidney failure
- •Acute or chronic infections (including HIV)
- •Serious pathologies (such as cancer, spondylolisthesis, rheumatoid arthritis or ankylosing spondylitis)
- •Symptoms of cervical spinal stenosis (such as incoordination of hands, arms and legs, bowel and bladder incontinence)
- •Radix compression (such as sensory changes, muscle weakness or decreased reflexes)
- •Whiplash or a history of cervical surgery
Outcomes
Primary Outcomes
Pain Pressure Threshold
Time Frame: Pain Pressure Threshold assessment will take maximum of 5 minutes.
Pressure Pain Threshold will be measured with the JTech Commander Algometer at the level of the right and left zygapophyseal joint of the dysfunctional cervical segment detected during physical examination. During the evaluation, the participants will be asked to lie in a prone position. By placing the probe of the algometer vertically on the skin, the pressure applied will be gradually increased and the participant will be asked to report at the first moment of pain. The measurement will be made once and the result will be recorded in kilograms.
Cervical Range of Motion
Time Frame: Cervical Range of Motion assessment will take maximum of 5 minutes.
Cervical Range of Motion will be assessed by Baselşne Bubble Inclinometer as degree of flexion-extension, rotation and lateral flexion and will be recorded.
Neuropeptide Measurement
Time Frame: Blood Sample Collection for Neuropeptide Measurement will take maximum of 5 minutes.
Neuropeptide Measurement will be performed as a result of evaluating the blood samples taken from the participants with the appropriate ELISA kits. Orexin A and Neurotensin levels are planned to be evaluated with Human Orexin A (Competitive EIA) ELISA Kit and Human NTS / NT / Neurotensin (Competitive EIA) ELISA Kit which are specific for these neuropeptides.
Secondary Outcomes
- Pain Intensity Measurement(Pain Intensity Measurement will take maximum of 1 minute.)
- Neck Disability(Neck Disability measurement will take maximum of 1 minute.)
Investigators
Mücahit ÖZTOP
Research Assistant
Pamukkale University