Randomized double-blind comparative study on the effect of bifidobacteria on the induction of resistance to hen's egg allergy oral immunotherapy
Not Applicable
- Conditions
- hen's egg allergy
- Registration Number
- JPRN-UMIN000030379
- Lead Sponsor
- showa university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
a) Of control poor atopic dermatitis or bronchial asthma b) Cardiovascular, Cranial nerve, Renal urology, Hepatobiliary, pancreatic, pancreatic, gastrointestinal, etc, which are serious or have diseases which may affect research c) Implementing other immunotherapy d) Other test responsibilities(shared)Patients judged inappropriate by the doctor as subjects
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Acquisition rate of egg tolerance at 52 weeks after intervention started
- Secondary Outcome Measures
Name Time Method Egg tolerance acquisition rate at 48 weeks after intervention started Objective indicator (blood: change in eosinophil count, total IgE, antigen specific IgE (egg egg: egg white, egg yolk, ovomucoid), antigen specific IgG4 (egg white, ovomucoid), basophil stimulation test (OVM) , Faeces: intestinal flora, calprotectin, skin,prick test) Side reaction rate on oral immunotherapy Safety assessment (incidence of adverse events)