Changes in Cerebral Oxygenation Studies Carried Out With the Use of Non-invasive Time-resolved Near-infrared Spectroscopy Device in Patients Undergoing Laparoscopy Procedure
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Increase in Intra-abdominal Pressure
- Sponsor
- Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences
- Enrollment
- 17
- Primary Endpoint
- Distribution of time of flight of photons
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The motivation results from the fact, that an intra-abdominal pressure is correlated with cerebral perfusion, in a mechanism of reducing venous outflow. Moreover, elevated intra-abdominal pressure leads to increase in intracranial pressure and decrease of cerebral perfusion pressure.
The main aim of the study was to investigate an influence of increase in intra-abdominal pressure on cerebral oxygenation measured with the use of non-invasive optical technique.
Detailed Description
The investigators applied time resolved near infrared spectroscopy device in order to estimate changes in hemoglobin concentration in a brain during gynecological procedure that involves laparoscopy. The optodes were positioned on a forehead on left and right hemisphere. The measurements were carried out during whole medical procedure, including anesthesia, start and stop of insufflation of abdominal cavity with carbon dioxide (CO2), surgical procedure, release of CO2 and waking up a patient. In those studies the special emphasis was put on a period of insufflation of abdominal cavity with CO2.
Investigators
Eligibility Criteria
Inclusion Criteria
- •laparoscopic procedure
Exclusion Criteria
- •no consent
Outcomes
Primary Outcomes
Distribution of time of flight of photons
Time Frame: 90 minutes (typically)
Distribution of time of flight of photons measured at 2 wavelengths, 690 nm and 830 nm and at 2 spots on a forehead
Secondary Outcomes
- Cerebral oxygenation(90 minutes (typically))
- Fluctuations of changes in Hb and HbO2 concentrations(90 minutes (typically))