changes in brain oxygen during position for neurosurgery

Not Applicable

Conditions: Health Condition 1: G978- Other intraoperative and postprocedural complications and disorders of nervous system

Lead Sponsor: Sree Chitra Tirunal Institute for Medical Sciences and Technology TRIVANDRUM

Recruitment & Eligibility

Inclusion Criteria

1.Consenting neurosurgical adult patients with age 18-60 years

2.ASA (American Society of Anaesthesiologists) status I and II patients.

3.Age 18â??60 years.

4.GCS of 15

Exclusion Criteria

1.Patient refusal.

2.Age less than 18 years and more than 60 years.

3.GCS <15

4.Longstanding diabetes mellitus, hypertension, vascular diseases, COPD (chronic obstructive

pulmonary disease).

5.Known case of cardiac illness (coronary heart disease, valvular heart disease, congenital

heart disease, congestive heart failure).

6.Patients with previous history of stroke, Transient ischemic attacks, carotid disease, severely increased ICP.

7.Obesity.

8.ASA (American Society of Anaesthesiologists) status III ,IV,V patients.

9.Patients with sub-arachnoid hemmorhage, vasospasm.

10.Pregnant & nursing mothers.

Primary Outcome Measures

Name	Time	Method
To assess the effect of change in position from supine to lateral and supine to prone on <br/ ><br>cerebral oxygenation using NIRS during various positions (supine, prone, lateral) used <br/ ><br>during elective neurosurgery.Timepoint: Baseline NIRS reading will be taken in supine position from NIRS <br/ ><br>electrodes placed at the frontal area. NIRS reading will be taken at 5 minutes after induction of anesthesia. <br/ ><br>One minute before positioning the patient NIRS value will again be noted. Post final positioning <br/ ><br>of the patient, NIRS values will be recorded every minute till first 10 minutes, and then every 5 <br/ ><br>minutes till 30 minutes.

Secondary Outcome Measures

Name	Time	Method
1. To assess the significance and causes of changes in cerebral oxygenation during patient <br/ ><br>positioning in neurosurgery. <br/ ><br>2. To assess changes in NIRS from awake state to anesthesia and positioning.Timepoint: Baseline NIRS reading will be taken in supine position from NIRS <br/ ><br>electrodes placed at the frontal area. NIRS reading will be taken at 5 minutes after induction of anesthesia. <br/ ><br>One minute before positioning the patient NIRS value will again be noted. Post final positioning <br/ ><br>of the patient, NIRS values will be recorded every minute till first 10 minutes, and then every 5 <br/ ><br>minutes till 30 minutes.