The effect of a dietary intervention with rice bran on intestinal health among adults at high risk of colorectal cancer

Not Applicable

Completed

• Conditions: Digestive health in healthy adults at high risk of colorectal cancer; Digestive System

• Registration Number: ISRCTN33245212
• Lead Sponsor: Chinese University of Hong Kong

Brief Summary

2021 Results article in https://doi.org/10.3390/nu13020526 (added 23/11/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-11-25
• Study Completion: 2020-11-30
• Last Update Posted: 29 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Chinese aged 50 or above
2. Categorised as a high risk group for the development of CRC (score 4-7) by the Asian-Pacific Colorectal Screening tool (APCS)
3. No gastrointestinal symptoms suggestive of colorectal cancer
4. Negative fecal occult blood test or negative colonoscopy findings for CRC within 1 year
5. No history of food allergy
6. No dietary restriction
7. Not currently taking cholesterol-lowering medications
8. Not currently taking non-steroidal anti-inflammatory drugs (NSAIDs)
9. No probiotic and prebiotics use for the past 3 months
10. No history of gallstones
11. No Chinese medicine use (except traditional Chinese soup) for the past 3 months
12. No antibiotic taking for the past 3 months

Exclusion Criteria

1. Having lower gastrointestinal symptoms in the past week
2. Currently pregnant unless sterilization was done or in menopause or lactating (self-reported by the participants)
3. Diagnosed to have diabetes mellitus

Study & Design

• Study Type: Interventional
• Study Design: Not specified