A pilot study to evaluate the effect of colchicine treatment on NSAID-induced small intestinal damage
Not Applicable
- Conditions
- SAID-induced small intestinal damage
- Registration Number
- JPRN-UMIN000026828
- Lead Sponsor
- Department of Gastroenterology, Osaka City University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 8
Inclusion Criteria
Not provided
Exclusion Criteria
1) Malignant tumor or severe systemic disease (CNS disase or psychiatric disease) 2) Crohns disease, intestinal tuberculosis, or known gastrointestinal stricture 3) Unable to swallow the video capsule 4) Pacemaker 5) Concomitant use of antibiotics 6) Severe liver disease 7) Severe renal disease 8) Hypersensitivity for colchicine 9) Pregnant or lactating women 10) Active small bowel bleeding (Patients with endoscopic hemostasis or intravascular embolization can be enrolled.) 11) Inadequate judged by PI
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete healing rate of small intestinal erosions and ulcers in 8 weeks of colchicine administration
- Secondary Outcome Measures
Name Time Method