Comparison of burprenorphine and morphine an adjuvant to 0.25% bupivacaine for post operative analgesia with ultrasound guided transversus abdominal plane block in cesarean delivery.
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Heart rate,
研究概览
简要总结
Post operative pain in cesarean delivery is of utmost concern, inadequate pain relief may lead to Poor recovery and prolong hospital stay. Hence it require a multimodal approach, as transversus abdominis plane has extended course of subcostal, ilioinguinal, iliohypogatric and genitofemoral nerves.A transversus abdominis plane (TAP) block is more appropriate in lower abdominal surgeries.As blind injections can result in inadvertent injury to bowel or blood vessels using ultrasound guided transversus abdominis plane block is more is more appropriate. Bupivacaine has shown its efficacy in providing post operative analgesia for 6 to 8hours adding an adjuvant will prolong its effect.In this study we are about to compare the post operative analgesic effect of buprenorphine and morphine when added as adjuvant to 0.25% bupivacaine in ultrasound guided transversus abdominis plane block, in patient undergoing cesarean delivery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Stratified block randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- Female
入选标准
- •Patient with ASA physical status-2 posted for cesarean delivery.
排除标准
- •Chronic pain disorder
- •Known allergy or hypersensitivity to the study drug
- •Coagulopathy 4.local infection at block site 5.patient refusal for the procedure.
结局指标
主要结局
Heart rate,
时间窗: All these parameters are measured every 15mins for 1st hour,then every hourly upto 12hours,Then every 4th hourly upto 24hours.
Post operative pain assessment (VAS score),
时间窗: All these parameters are measured every 15mins for 1st hour,then every hourly upto 12hours,Then every 4th hourly upto 24hours.
Respiratory rate,
时间窗: All these parameters are measured every 15mins for 1st hour,then every hourly upto 12hours,Then every 4th hourly upto 24hours.
Blood pressure,
时间窗: All these parameters are measured every 15mins for 1st hour,then every hourly upto 12hours,Then every 4th hourly upto 24hours.
Oxygen saturation.
时间窗: All these parameters are measured every 15mins for 1st hour,then every hourly upto 12hours,Then every 4th hourly upto 24hours.
次要结局
- 24 hour analgesic consumption, nausea, vomiting, pruritis,(Monitored for 24 hours)