Prospective Study of Pain After Spinal Morphine for Cesarean Section and Analysis of Factors Involved in Moderate to Severe Pain
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pain, Postoperative
- Sponsor
- Mahidol University
- Enrollment
- 660
- Locations
- 1
- Primary Endpoint
- Incidence of moderate to severe pain
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Spinal block with intrathecal morphine is a popular anesthetic technique in cesarean delivery. This technique brings about good maternal and neonatal outcomes as well as provides good postoperative pain control. Systematic review showed intrathecal morphine produced long period of pain control up to 27 hours. However, some patients still experienced moderate to severe pain which defined as postoperative pain score >,= 4. From our institute survey, there were more than 50 percents of patients undergoing cesarean delivery receiving spinal block with intrathecal morphine experienced moderate to severe pain in the first 24 hours.
The aim of the study is to determine the actual incidence and associated factors of patients whom experienced moderate to severe pain after spinal anesthesia with intrathecal morphine 200 mcg in cesarean delivery.
Detailed Description
Spinal block with intrathecal morphine is a popular anesthetic technique in cesarean delivery. This technique brings about good maternal and neonatal outcomes as well as provides good postoperative pain control. Systematic review showed intrathecal morphine produced long period of pain control up to 27 hours. However, some patients still experienced moderate to severe pain which defined as postoperative pain score \>,= 4. From our institute survey, there were more than 50 percents of patients undergoing cesarean delivery receiving spinal block with intrathecal morphine experienced moderate to severe pain in the first 24 hours. Failure in achieve adequate pain control results in poor maternal satisfaction, effect breast feeding and may lead to chronic wound pain. The aim of the study is to determine the actual incidence of patients whom experienced moderate to severe pain after spinal anesthesia with intrathecal morphine 200 mcg in cesarean delivery. Also, factors that may involved moderate to severe postoperative pain will be analyzed and reported.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age \> 18 years
- •Elective cesarean section
- •Patient accept spinal anesthesia
- •ASA classification I-II
- •Understand numerical rating scale for pain score
Exclusion Criteria
- •Not understand Thai
- •Contraindicated in spinal anesthesia with intrathecal morphine
- •Complicated pregnancy that general anesthesia may required for cesarean delivery
Outcomes
Primary Outcomes
Incidence of moderate to severe pain
Time Frame: The first 24 hours postoperatively
Incidence of moderate to severe pain, pain score \>,= 4
Secondary Outcomes
- Incidence of moderate to severe pain in the 2nd postoperative day(Form 24 hours to 48 hours postoperatively)
- Factors associated with moderate to severe pain(The first 24 hours postoperatively)