Skip to main content
Clinical Trials/NCT05890079
NCT05890079
Completed
Not Applicable

External Oblique Intercostal Plane Block for Postoperative Analgesia in Living Liver Donors

Istinye University1 site in 1 country64 target enrollmentMay 8, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Liver Transplantation
Sponsor
Istinye University
Enrollment
64
Locations
1
Primary Endpoint
Morphine consumption
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Postoperative pain management is one of the important factors to improve rehabilitation and enhance recovery. External oblique intercostal plane block may be used for abdominal wall analgesia to provide effective analgesia for abdominal surgery. The aim of this study is to investigate the postoperative analgesic efficacy of external oblique intercostal plane block and subcostal transversus abdominis plane block in living liver donors.

Researchers will compare the external oblique intercostal plane block group with subcostal transversus abdominis plane block to see if the external oblique intercostal plane block is effective for postoperative analgesia in living liver donors.

Detailed Description

Patients scheduled for living donor hepatectomy will be separated into 2 groups: Subcostal Transversus Abdominis Plane Block Group and External Oblique Intercostal Plane Block Group. Patients in Subcostal Transversus Abdominis Plane Block will be performed subcostal transversus plane block at the end of the surgery and after skin closure and received patient controlled analgesia with morphine for postoperative analgesia. Patients in External Oblique Intercostal Plane Block Group will be performed bilateral External Oblique Intercostal Plane Block at the end of the surgery and after skin closure and received patient controlled analgesia with morphine for postoperative analgesia. Morphine consumption for first postoperative 24 hours, visual analog scale scores, time to need for first rescue analgesia, amount of rescue analgesic drug, incidence of postoperative nausea and vomiting will be recorded.

Registry
clinicaltrials.gov
Start Date
May 8, 2023
End Date
January 17, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age between 18 and 75 years
  • Patients with American Society of Anesthesiology (ASA) physical status I-II
  • Patients scheduled for a living donor hepatectomy

Exclusion Criteria

  • Allergy to local anesthetics
  • Coagulopathy
  • Skin infection at the block area
  • Advanced renal failure
  • Chronic pain syndromes
  • Alcohol or drug abuse
  • Psychiatric disorders

Outcomes

Primary Outcomes

Morphine consumption

Time Frame: Postoperative 24 hours

The amount of morphine required by the patient and given by the device will be recorded for the first 24 hours.

Secondary Outcomes

  • Postoperative visual analog scale scores(Postoperative 24 hours)
  • Rescue analgesic drug consumption(postoperative 24 hours)
  • Incidence of postoperative nausea and vomiting(postoperative 24 hours)

Study Sites (1)

Loading locations...

Similar Trials