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临床试验/NCT05890079
NCT05890079已完成不适用

External Oblique Intercostal Plane Block for Postoperative Analgesia in Living Liver Donors

Istinye University1 个研究点 分布在 1 个国家目标入组 64 人开始时间: 2023年5月8日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
64
试验地点
1
主要终点
Morphine consumption

研究概览

简要总结

Postoperative pain management is one of the important factors to improve rehabilitation and enhance recovery. External oblique intercostal plane block may be used for abdominal wall analgesia to provide effective analgesia for abdominal surgery. The aim of this study is to investigate the postoperative analgesic efficacy of external oblique intercostal plane block and subcostal transversus abdominis plane block in living liver donors.

Researchers will compare the external oblique intercostal plane block group with subcostal transversus abdominis plane block to see if the external oblique intercostal plane block is effective for postoperative analgesia in living liver donors.

详细描述

Patients scheduled for living donor hepatectomy will be separated into 2 groups: Subcostal Transversus Abdominis Plane Block Group and External Oblique Intercostal Plane Block Group. Patients in Subcostal Transversus Abdominis Plane Block will be performed subcostal transversus plane block at the end of the surgery and after skin closure and received patient controlled analgesia with morphine for postoperative analgesia. Patients in External Oblique Intercostal Plane Block Group will be performed bilateral External Oblique Intercostal Plane Block at the end of the surgery and after skin closure and received patient controlled analgesia with morphine for postoperative analgesia. Morphine consumption for first postoperative 24 hours, visual analog scale scores, time to need for first rescue analgesia, amount of rescue analgesic drug, incidence of postoperative nausea and vomiting will be recorded.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age between 18 and 75 years
  • Patients with American Society of Anesthesiology (ASA) physical status I-II
  • Patients scheduled for a living donor hepatectomy

排除标准

  • Allergy to local anesthetics
  • Coagulopathy
  • Skin infection at the block area
  • Advanced renal failure
  • Chronic pain syndromes
  • Alcohol or drug abuse
  • Psychiatric disorders

研究组 & 干预措施

Subcostal transversus abdominis plane block group

Active Comparator

The patients in subcostal transversus abdominis plane block group will be received subcostal transversus abdominis plane block and patient controlled analgesia with morphine for postoperative analgesia

干预措施: Subcostal transversus abdominis plane block (Other)

External oblique intercostal plane block group

Active Comparator

The patients in External oblique intercostal plane block group will be received external oblique intercostal plane block and patient controlled analgesia with morphine for postoperative analgesia

干预措施: External oblique intercostal plane block (Other)

结局指标

主要结局

Morphine consumption

时间窗: Postoperative 24 hours

The amount of morphine required by the patient and given by the device will be recorded for the first 24 hours.

次要结局

  • Postoperative visual analog scale scores(Postoperative 24 hours)
  • Rescue analgesic drug consumption(postoperative 24 hours)
  • Incidence of postoperative nausea and vomiting(postoperative 24 hours)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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