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Analysis of Injectate Spread During Erector Spinae Block

Not Applicable
Completed
Conditions
Cervical
Pain
Interventions
Procedure: Erector spinae plane block
Registration Number
NCT05280847
Lead Sponsor
Keimyung University Dongsan Medical Center
Brief Summary

The primary purpose of this study was to identify the ESPB spread level in the craniocaudal direction when performed at the T2 level. The secondary purpose was to determine the incidence of spread into epidural, paravertebral, intercostal, and intravascular injections with ESPB

Detailed Description

The ESPB requires ultrasound guidance which enables visible local anesthetic spread underneath the erector spinae muscles. The spinalis, longissimus thoracis, and iliocostalis muscles comprise the ES muscles, which run vertically along both sides of the vertebral column from the sacrum up to the skull base. The ESPB can be performed in the cervical, thoracic, and lumbar regions. Among them, upper or mid thoracic ESPB has been used more widely compared to cervical and lumbar regions. Previous cadaveric studies on the ESPB at the T5 level using computed tomography (CT) reconstruction or direct dissection demonstrated the extensive craniocaudal distribution of methylene blue ranging from T1 to T8 vertebral segments deep to the ES muscles and variable involvement of epidural, paravertebral, and intercostal spaces. The ESPB performed at the T2 level of the cadaver demonstrated an injected dye distribution ranging from C4 to T10. Also, 36% of cadavers showed the spread of an injected dye to the ventral, dorsal ramus, paravertebral space, and even the contralateral side. The exact mechanism of action of ESPB remains unclear. A recent study suggested that the analgesic effect of ESPB could be obtained by blocking the ventral and dorsal ramus of the spinal nerves by passing through the costotransverse foramen. However, in clinical practice, we can encounter highly variable clinical outcomes or sensory block after the ESPB. The study of the physical spread of the injected agent can be used to predict the clinical result and elucidate the possible mechanism of action of ESPB.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
159
Inclusion Criteria
  • Cervical facet joint arthrosis
  • Cervical foraminal stenosis
  • Cervical herniated intervertebral disc
  • myofascial pain syndrome of upper back muscle
Exclusion Criteria
  • Allergy to local anesthetics or contrast medium
  • Pregnancy
  • Prior history of cervical spine surgery
  • Coagulation abnormality

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
20 ml ESP groupErector spinae plane blockESP group using 20 ml mixture of local anesthetics and contrast medium using ultrasound and fluoroscopy
10 ml ESP groupErector spinae plane blockESP group using 10 ml mixture of local anesthetics and contrast medium using ultrasound and fluoroscopy
Primary Outcome Measures
NameTimeMethod
spread level in the cranio-caudal directionbaseline, 1 minutes after erector spinae plane block

fluoroscopic contrast medium spread level in the cranio-caudal direction

Secondary Outcome Measures
NameTimeMethod
Number of participant showing paravertebral spreadbaseline, 1 minute after erector spinae plane block

Number of participant showing paravertebral spread by analysis of fluorosocpic image

Number of participant showing intercostal spreadbaseline, 1 minute after erector spinae plane block

Number of participant showing intercostal spread by analysis of fluoroscopic image

Number of participant showing epidural spreadbaseline, 1 minute after erector spinae plane block

Number of participant showing epidural spread by analysis of fluoroscopic image

Number of participant showing intravascular spreadbaseline, 1 minute after erector spinae plane block

Number of participants showing intravascular spread by analysis of fluoroscopic image

Trial Locations

Locations (2)

Hong ji HEE

🇰🇷

Daegu, Korea, Republic of

Ji Hee Hong

🇰🇷

Daegu, Korea, Republic of

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