Preoperative Assessment of Aortic Valve Stenosis and Coronary Artery Disease: Dual-source Computed Tomography Compared With Invasive Coronary Angiography and Transthoracic Echocardiography

Luzerner Kantonsspital1 site in 1 country65 target enrollmentMay 2007

ConditionsAortic Valve Stenosis Coronary Disease

Overview

Phase: N/A
Intervention: Not specified
Conditions: Aortic Valve Stenosis
Sponsor: Luzerner Kantonsspital
Enrollment: 65
Locations: 1
Primary Endpoint: Quality of cardiac imaging in computed tomography
Last Updated: 13 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

We sought to determine whether the dual-source computed tomography assessment of aortic valve stenosis and coronary artery disease is equivalent to or even better than conventional invasive coronary angiography and transthoracic echocardiography.

Detailed Description

Until now invasive coronary angiography has established itself for the assessment of symptomatic aortic valve stenosis. Literature shows a good correlation between MSCT, MRI, TTE and TEE for evaluating the severity of the aortic valve stenosis. The dual-source computed tomography (DSCT) is capable of assessing coronary arteries with a high sensitivity and specificity in term of relevant stenosis (\>50%), due to its excellent spatial and temporal resolution. This study includes the assessment of patients with symptomatic valve stenosis. The severity of the aortic valve stenosis is being assessed by DSCT and TTE. Significant coronary artery stenosis and its localisation are assessed by DSCT and invasive coronary angiography. We examine the correlation between DSCT on one side and either TTE or invasive coronary angiography on the other.

Registry

clinicaltrials.gov

Start Date

May 2007

End Date

December 2013

Last Updated

13 years ago

Study Type

Interventional

Study Design

Single Group