The Stockholm CREAtinine Measurements (SCREAM) Project
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 3,200,000
- 主要终点
- Adverse health events by levels of kidney function
研究概览
简要总结
The Stockholm CREAtinine Measurements (SCREAM) project is a healthcare utilization cohort including, at present, all adult residents in Stockholm between 2006 and 2021. The region of Stockholm had a population of 2.3 million citizens in 2021and provides universal healthcare with a single unified health-system. Administrative databases with complete information on socidemographic data, healthcare use, diagnoses and therapeutic/surgical procedures, and vital status were enriched with performed laboratory tests, dispensed prescriptions at Swedish pharmacies and validated kidney replacement therapy endpoints. Registries were linked and de-identified by the Swedish National Board of Welfare and are considered to have no or minimal loss to follow-up. Because the study utilized de-identified data, it was deemed not to require informed consent and was approved by the regional ethical review boards and the Swedish National Board of Welfare.
For detailed description of available data and linked registers please consult:
详细描述
Please consult cohort description in:
https://pubmed.ncbi.nlm.nih.gov/35028991/ https://pubmed.ncbi.nlm.nih.gov/26798472/
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 0 Years 至 110 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •For both cohorts:
- •Be a resident of Stockholm during 2006-2021, of all ages
- •For the primary cohort:
- •To have undertaken at least one test of serum creatinine or albuminuria during 2006-
- •If this condition is met, we will then extract a broad range of laboratory tests
- •For the secondary cohort:
- •Anyone not undertaking a test of serum creatinine or albuminuria will conform the secondary cohort. In this cohort we will not extract any other laboratory test, but will obtain the rest of healthcare information
- •Exclusion criteria:
排除标准
- 未提供
结局指标
主要结局
Adverse health events by levels of kidney function
时间窗: 2006-2021
multiple outcomes evaluated such as cardiovascular events, fractures, dementia, cancer, etc, all of them based on claims data and/or laboratory data
Effect of medications or conditions on kidney function decline
时间窗: 2006-2021
Evaluation of changes in kidney function over time upon occurrence of a certain condition (i.e., heart failure or covid19 infection) or initiation of a specific medication
Safety and efficacy of medications by levels of kidney function
时间窗: 2006-2021
multiple outcomes evaluated depending on the treatments of interest, all of them based on claims data and/or laboratory data
次要结局
- Adverse health events associated to laboratory abnormalities(2006-2021)
研究者
Juan Jesus Carrero
Professor of Cardiorenal Epidemiology
Karolinska Institutet