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Clinical Trials/NCT06620211
NCT06620211
Completed
Not Applicable

Evaluation of the Safety, Performance, and Tolerability of the Sacromesh® Medical Device in the Treatment of Prolapse by Promontofixation in a Population of Patients Followed Over the Long Term.

Cousin Biotech1 site in 1 country290 target enrollmentApril 23, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Prolapse; Female
Sponsor
Cousin Biotech
Enrollment
290
Locations
1
Primary Endpoint
RATE AND TYPE OF REINTERVENTION
Status
Completed
Last Updated
last year

Overview

Brief Summary

An observational, multicenter study with retrospective recruitment and two data collection methods, one retrospective (medical records) and the other prospective (questionnaires).

Patients who meet the inclusion criteria and have none of the non-inclusion criteria will be selected using the computer database of each investigating center. Data from consultation visits and surgery data will be collected and filled in the observation books.

The patient will be contacted by the investigators to collect data on quality of life and the existence or absence of pain associated with implant placement at follow-up.

Registry
clinicaltrials.gov
Start Date
April 23, 2020
End Date
October 19, 2023
Last Updated
last year
Study Type
Observational
Sex
Female

Investigators

Sponsor
Cousin Biotech
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • The inclusion criteria for participation in the study are as follows:
  • Patient who underwent surgery to place the Sacromesh® medical device for a prolapse cure, between 2009 and 2018 in one of the investigation centres participating in the study.
  • Patient who has read the information note and has not formulated an -opposition.
  • Adult patient with full mental capacity/capability

Exclusion Criteria

  • Patient under guardianship or curatorship
  • Patient hospitalized at time of inclusion
  • Patient with an adjacent pathology that may strongly interfere with her quality of life and VAS score.
  • Patients with mental psychological pathology

Outcomes

Primary Outcomes

RATE AND TYPE OF REINTERVENTION

Time Frame: 2020 - 2023

safety assessment of Sacromesh® implan through the documentation, within the French healthcare context, of the rate and type of re-interventions after Sacromesh® implantation. Collection and documentation of the nature and frequency of reinterventions after placement of the Sacromesh® device, including causes and nature of eventual explants, be it total or partial. The rate of re intervention will be calculated using Yes/No answer to POP recurrence question in the CRF. Yes answer to the question will be considered as a re intervention. In case of any POP recurrence investigator was asked to fill an adverse event form to describe the re intervention. Type of re intervention will be derived from AE form into a two classes categorical variable taking either 'De novo prolapse (recurrence, vaginal extrusion)' or 'Other' value. Both rate of re intervention and type of re intervention will be described as qualitative variables.

Secondary Outcomes

  • evaluation the tolerance of the Sacromesh® implant Rate and type of postoperative complications(2020 - 2023)
  • evaluation the tolerance of the Sacromesh® implant qol(2020 - 2023)
  • evaluation the tolerance of the Sacromesh® implant postoperative pain(2020 - 2023)

Study Sites (1)

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