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Clinical Trials/NCT02733393
NCT02733393
Completed
Phase 1

Sphenopalatine Ganglion Block to Treat Shoulder Pain After Thoracotomy- An Open Label Pilot Study

NYU Langone Health1 site in 1 country2 target enrollmentSeptember 2015

Overview

Phase
Phase 1
Intervention
Sphenopalatine Ganglion (SPG) Block
Conditions
Ipsilateral Shoulder Pain
Sponsor
NYU Langone Health
Enrollment
2
Locations
1
Primary Endpoint
Shoulder Pain Reduction
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

The purpose of this pilot study is to evaluate the utility of sphenopalatine ganglion (SPG) block to manage ipsilateral shoulder pain (ISP) after thoracotomy. This will be an open label preliminary pilot study to determine if SPG block has potential utility to manage ISP in post-thoracotomy patients. The primary outcome variable will be reduction of shoulder pain.

Detailed Description

This is an open label preliminary pilot study which will evaluate the utility of sphenopalatine ganglion (SPG) block to manage ipsilateral shoulder pain (ISP). It will determine if SPG block has potential utility to manage ISP in post-thoracotomy patients One hundred (100) patients will initially be consented in this study. Patients have to develop ISP and have a pain VAS \>= 5. The study is seeking ten (10) eligible participants. Patients will be followed after the SPG block(s), and the duration of pain relief will be monitored by serial assessments of the VAS. This assessment will occur for the initial SPG block and for all follow-up blocks, if performed. The follow-up assessments will only involve having the patient rate the ISP using a verbal VAS; This will take less than a minute of patients time. In addition, all patients will have PRN access to standard systemic analgesics as routinely ordered by the surgical service Safety assessments will be performed on all subjects. Blood pressure, heart rate and respiratory rate will be obtained every 15 minutes after each SPG block for 90 minutes. Dr. Grant will monitor the subjects for 90 minutes after each SPG block.

Registry
clinicaltrials.gov
Start Date
September 2015
End Date
September 5, 2017
Last Updated
8 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Any type of open thoracotomy or video-assisted thoracoscopic surgery (VATS)
  • Presence of post-operative ISP, VAS\>5/10
  • American Society of Anesthesiologists Class 1 - 4
  • No allergy to lidocaine

Exclusion Criteria

  • American Society of Anesthesiologists Class 5
  • Allergy to lidocaine
  • Nasal pathology (e.g., deviated septum)
  • Bleeding diathesis
  • Any patient who the PI feels will be unable to comply with all protocol related procedures
  • Shoulder pain prior to thoracotomy

Arms & Interventions

SPG Block

Intervention: Sphenopalatine Ganglion (SPG) Block

SPG Block

Intervention: lidocaine

Outcomes

Primary Outcomes

Shoulder Pain Reduction

Time Frame: 90 Minutes

Patients will be followed after the SPG block(s) and the duration of pain relief will be monitored by serial assessments of the VAS. This assessment will occur for the initial SPG block and for all follow-up blocks, if performed.

Study Sites (1)

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