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Clinical Trials/NCT02809755
NCT02809755
Withdrawn
Phase 4

Sphenopalatine Ganglion Block to Prevent Shoulder Pain After Laparoscopic Bariatric Surgery

NYU Langone Health1 site in 1 countryAugust 8, 2016
ConditionsObesity
Interventions4% LidocaineSaline

Overview

Phase
Phase 4
Intervention
4% Lidocaine
Conditions
Obesity
Sponsor
NYU Langone Health
Locations
1
Primary Endpoint
Change in STP as assessed by Numeric Rating Scale (NRS-11), from before to after the treatment in the PACU after receiving a 30-minute unilateral SPG block or bilateral SPG block
Status
Withdrawn
Last Updated
7 years ago

Overview

Brief Summary

The purpose of this study is to determine the efficacy of sphenopalatine ganglion (SPG) block to prevent shoulder tip pain following primary laparoscopic gastric banding, band revision, band replacement, primary sleeve gastrectomy or revision of sleeve gastrectomy. Shoulder tip pain (STP) is a common problem after laparoscopic surgery, manifesting in the post-anesthesia care unit and for days or possibly weeks thereafter (Dixon 2005). Systemic analgesics including opioids and non-steroidal anti-inflammatory drugs (NSAIDs) do not reliably relieve STP. This study is designed to determine if the SPG block, a simple and low-risk procedure, effectively treats STP after laparoscopic bariatric surgery.

Detailed Description

This is a randomized, placebo-controlled, parallel group prospective, double-blind study. The primary outcome variable will be change in STP from \> 4 before to after treatment in the PACU after primary laparoscopic gastric banding, band revision, band replacement, sleeve gastrectomy, or revision of sleeve gastrectomy. Investigators hope to achieve a decline in STP in 2 units after treatment.

Registry
clinicaltrials.gov
Start Date
August 8, 2016
End Date
April 3, 2017
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Elective primary laparoscopic gastric banding surgery.
  • Laparoscopic band revision surgery
  • Laparoscopic band replacement surgery.
  • Sleeve gastrectomy.
  • Revision of sleeve gastrectomy.
  • American Society of Anesthesiologists Class 2 or
  • No allergy to study drugs.
  • Facility with English language to allow compliance with study protocol.

Exclusion Criteria

  • American Society of Anesthesiologists Class 4 or
  • Allergy to lidocaine or to any local anesthetic
  • Allergy to oxymetazoline (Afrin)
  • Pregnancy
  • Bleeding diathesis
  • Known nasal pathology including active sinusitis
  • Previous nasal surgery
  • Preoperative anticoagulant use OTHER THAN aspirin 81 mg and/or heparin 5000 U SQ bid administered for DVT prophylaxis.
  • Acute psychiatric disease
  • History of chronic right or left shoulder pain

Arms & Interventions

4% lidocaine

10 mL vials filled with 4% lidocaine or normal saline (50 vials of each solution) and pharmacist will code the vials from 1 to 100 using a computer-generated randomization scheme.

Intervention: 4% Lidocaine

Placebo Saline

10 mL vials filled with 4% lidocaine or normal saline (50 vials of each solution) and pharmacist will code the vials from 1 to 100 using a computer-generated randomization scheme.

Intervention: Saline

Outcomes

Primary Outcomes

Change in STP as assessed by Numeric Rating Scale (NRS-11), from before to after the treatment in the PACU after receiving a 30-minute unilateral SPG block or bilateral SPG block

Time Frame: Baseline, 30 Minutes

subject will be asked to rate her/his pain from zero to ten with zero being "no pain" to ten being "the worst pain imaginable."

Study Sites (1)

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