Treatment of severe fatigue after stroke. A study of cognitive therapy and physical exercise training in eight rehabilitation centres in the Netherlands.
Completed
- Conditions
- Post-stroke fatigueCognitive Rehabilitationgraded activityCVAvermoeidheidcognitieve revalidatie
- Registration Number
- NL-OMON21507
- Lead Sponsor
- The principal initiator for the study and promotor is:Prof. dr. L. FasottiDonders Insitute for Brain, Cognition and Behaviour. Radboud University Nijmegen, The Netherlands
- Brief Summary
Cognitive and Graded Activity Training Can Alleviate Persistent Fatigue After Stroke: A Randomized, Controlled Trial.<br> Aglaia M.E.E. Zedlitz, MSc; Toni C.M. Rietveld, PhD; Alexander C. Geurts, MD, PhD; Luciano Fasotti, PhD<br> Stroke. 2012; 43: 1046-1051 Published online before print February 2, 2012, doi: 10.1161/​STROKEAHA.111.632117
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 96
Inclusion Criteria
1. Post-onset of stroke at least 4 months;
2. Age between 18 and 70 years;
Exclusion Criteria
1. Severe cognitive impairments (severe neglect, severe memory problems, severe planning problems, denial of illness);
2. Psychopathology (clinical interview and HADS-depression score >10);
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fatigue severity (Checklist Individual Strength, fatigue severity score).
- Secondary Outcome Measures
Name Time Method 1. Psychosocial well-being (SCL-90 & HADS);<br /><br>2. Functional impairments (SA-SIP-30);<br /><br>3. Physical condition (6 minute walking test);<br /><br>4. Activity (actometers & registration);<br /><br>5. Attention (SART & ANT);<br /><br>6. Memory (RMBT & CVWLT);<br /><br>7. Cognitive complaints (CIS-C, CFQ);<br /><br>8. Coping (CISS);<br /><br>9. Attribution (SES & FCS);<br /><br>10. Social support (SSL).