A Randomized Comparative Study Between Dexmedetomidine 100 And Clonidine 150 As Adjuvant To Ropivacaine In Ultrasound Guided Adductor Canal Block For TKR Surgeries
- Conditions
- Unilateral primary osteoarthritisof knee,
- Registration Number
- CTRI/2021/09/036159
- Lead Sponsor
- Sanjay Gandhi Institute Of Trauma And Orthopedics
- Brief Summary
•Lowerlimb surgeries can be performed under satisfactory anesthetic conditions usinggeneral, regional and peripheral nerve block anesthesia. Yet postoperative painand anesthetic side effects remain a problem.
•Theadductor canal block, beingsegmental in nature, can be expected to produce some advantages regardinghemodynamic stabilityandmay be a viable alternative to other techniques.
•Adductorcanalblock involves the unilateral administration of local anesthetics to the nerveswithout interveningcentral nervous system.
•Thisprocedureallows avoiding the useof poly pharmacy and also can be used as an alternative method in patientswith unstable cardiovascular systems
Primary objectives:
•Tocompare efficacy of Clonidine and Dexmedetomedine as adjuvant to 0.2%Ropivacaine in adductorcanal block for knee arthroscopic surgeries, with respect to
•Onset ofsensory block
• Durationof sensory blockade
• Totalrescue analgesia consumption in the first 24hrs.
Secondary objectives
•Hemodynamicparameters
• Adverseeffects, if any.
• Cardiovascularor neurological complications if any
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 100
- 1)ASA I to III patients of either sex.
- 2)Undergoing unilateral total knee replacement surgeries.
- 1)Patients with a history of allergy to local anesthetics.
- 2)Patients with history of mental dysfunction.
- 3)Patient refusal.
- 4)Morbid obesity, coagulopathy and significant cardiovascular, respiratory, renal, hepatic or metabolic disease or CNS disorders.
- 5)Infection at site of procedure.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)Onset of sensory block 1 day 2)Duration of sensory blockade 1 day 3)Total rescue analgesia consumption in the first 24hrs. 1 day
- Secondary Outcome Measures
Name Time Method adverse reactions if any 24 hrs
Trial Locations
- Locations (1)
Sanjay Gandhi Institute of Trauma and Orthopedics
🇮🇳Bangalore, KARNATAKA, India
Sanjay Gandhi Institute of Trauma and Orthopedics🇮🇳Bangalore, KARNATAKA, IndiaDr Bharath Kumar KPrincipal investigator9620422424drbharathkumar@gmail.com