A comparative study of intralesional novel triple therapy injection Vs steroid injection in the treatment of keloid

Not yet recruiting

• Conditions: Other hypertrophic disorders of the skin,

• Registration Number: CTRI/2024/01/061930
• Lead Sponsor: Aarupadai Veedu Medical College

Brief Summary

Keloids are benign dermal fibroproliferative nodular lesions that tends to arise

from skin trauma or other events.Many treatment modalities have been explored and have been reported

to be beneficial. Clinicians are conducting researches for refining the use of

common therapies (steroids & radiation). Anti-inflammatory and

chemotherapeutic molecules, procedural focused therapies (cryotherapy and

lasers), have also found a role in reducing keloid symptomatology. Despite the

growing literature investigating reliable methods for keloid management, there

are no standardized guidelines or treatment protocols supported by academic

governing bodies.Treatment of keloids seldom result in complete resolution of symptoms

and recurrence is commonly seen. Hence there is a need for novel treatment

modalities.In this study we aim to compare the efficacy of Novel Triple Medicine

Combination Injections Vs Triamcinolone Acetonide Injections for the

treatment of Keloid as a better treatment modality.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2024-01-24
• Study Start: 2024-05-02

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

• 1.Patients with keloids.
• 2.Age group of 15-65 years.
• 3.Both gender.
• 4.Consenting patients for the study.

Exclusion Criteria

• 1.Pregnancy and lactating women.
• 2.Heart Disease.
• 3.Liver And Kidney Disease.
• 4.Immunocompromised patients.
• 5.H/O Previous treatment.
• 6.Non-compliant patients.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The Vancouver Scar Scale Score	At Baseline 3weeks 9weeks 12 weeks & followed up further 3 months at monthly intervals
Primary outcome to assess treatment response	At Baseline 3weeks 9weeks 12 weeks & followed up further 3 months at monthly intervals

Secondary Outcome Measures

Name	Time	Method
Clinical Improvement based on Photographic Document	At Baseline 3weeks 9weeks 12 weeks & followed up further 3 months at monthly intervals

Trial Locations

Locations (1)

Aarupadai Veedu Medical College; 🇮🇳 Pondicherry, PONDICHERRY, India

Aarupadai Veedu Medical College

🇮🇳Pondicherry, PONDICHERRY, India

Sanjay Kumar Menon T

Principal investigator

9544100942

sanjaymenon2504@gmail.com