Investigating the preemptive effect of two different doses of dexmedetomidine on changes in blood pressure and heart rate following the use of a tourniquet during a randomized trial of upper extremity orthopedic surgery
Phase 3
Recruiting
- Conditions
- Condition 1: Blood pressure. Condition 2: Heart rate.
- Registration Number
- IRCT20090129001615N7
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
Patients with ASA (American Society of Anesthesiologists) = 1, aged 18-65 years, who are
Patients aged 18-65 years
Candidates for upper limb orthopedic surgery under tourniquet who undergo general anesthesia
Exclusion Criteria
Addicted people
People with a history of allergy to the studied drugs
People with heart, liver or kidney failure
People with ASA = 2
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood pressure. Timepoint: At baseline times (before administration of study drugs) and then at times 0, 10, 20, 30, 40, 50 and 60 minutes after tourniquet inflation and then immediately after deflation. Method of measurement: Sphygmomanometer.;Heart rate. Timepoint: At baseline times (before administration of study drugs) and then at times 0, 10, 20, 30, 40, 50 and 60 minutes after tourniquet inflation and then immediately after deflation. Method of measurement: Electrocardiogram.;Oxygen saturation. Timepoint: At baseline times (before administration of study drugs) and then at times 0, 10, 20, 30, 40, 50 and 60 minutes after tourniquet inflation and then immediately after deflation. Method of measurement: Pulse oximeter.
- Secondary Outcome Measures
Name Time Method