Evaluation of the effectiveness of a portal plexus Block in local ablation of hepatic malignancies

Phase 2

Recruiting

• Conditions: Patients with focal liver lesions of primary or secondary hepatic malignancies in whom a local ablation procedure will be carried out.; C78.7; C22.0; C22.1; Secondary malignant neoplasm of liver and intrahepatic bile duct; Liver cell carcinoma; Intrahepatic bile duct carcinoma

• Registration Number: DRKS00027881
• Lead Sponsor: niversitätsklinikum Magdeburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-01-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• primary and secondary malignancies of the liver
• male or female, 18+ years
• Written consent to participate in all study procedures

Exclusion Criteria

Contraindications for ablative procedures:
• Allergic reactions to contrast media or other substances to be injected
• Poor performance status (ECOG =2)
• Coagulation disorders
• Bilirubin> 30 µmol / l
• Symptoms of decompensated liver disease
• Acute infections, local or generalized
• Sepsis
• Hypovolemia
• Mechanical ileus
• Pathologies in the region around porta hepatis

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction of analgesic consumption (opioids, sedatives) during and after the intervention

Secondary Outcome Measures

Name	Time	Method
Pain reduction during and after the intervention