Effects of Intermittent Theta Burst Stimulation in Addition to Constraint-Induced Movement Therapy in Stroke Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Wolf-Motor Function Test
研究概览
简要总结
In recent studies, it has been reported that intermittent theta-burst stimulation (iTBS) provides additional benefits when applied in adjunct to the rehabilitation in all stages of stroke (acute, subacute, or chronic). In our study, it was aimed to evaluate the effectiveness of iTBS applied in addition to modified constraint-induced movement therapy (mCIMT). By doing so, we intend to increase patient adherence to neurorehabilitation and decrease the cost of rehabilitation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •First time and unilateral stroke
- •1-12 months after the incident
- •Getting 24 points or more in Mini Mental Status Examination
- •Being able to stand for 2 minutes without any help by using the upper extremity as a support tool when necessary.
- •Being a low-functioning patient according to the CIMT criteria: a) At least 10 degrees of active wrist extension starting from the angle of full flexion, b) 10 degrees of extension at the metacarpophalangeal and inter-phalangeal joints of at least 2 fingers
排除标准
- •those who score more than 2.5 points on the Motor Activity Log-28 scale,
- •who have severe pain in the upper extremity (5 and above on the Visual Analogue Scale) and spasticity (3 and above on the Modified Ashworth Scale), which may affect the treatment, and
- •Those who do not have adequate communication skills.
- •Patients who have visual problems
结局指标
主要结局
Wolf-Motor Function Test
时间窗: 45 minutes
It is a new time-based method to evaluate upper extremity performance while providing insight into joint-specific and total limb movements
Fugl-Meyer Assessment-Upper extremity
时间窗: 30 minutes
The Fugl-Meyer Assessment (FMA) is a stroke-specific, performance-based impairment index. It is designed to assess motor functioning, balance, sensation and pain.
次要结局
- Motor Evoked Potentials (MEPs)(10 minutes)
研究者
Esma Nur KOLBAŞI
Researcher
Istanbul Medeniyet University