Cerebellar Loops and Attention Deficit Hyperactivity Disorder (ADHD)

Not Applicable

Terminated

• Conditions: Attention Deficit Disorder With Hyperactivity

• Registration Number: NCT00684931
• Lead Sponsor: University Hospital, Bordeaux

Brief Summary

The aim of this study is to investigate the integrity of connectivity between the neocortex and the cerebellum in the Attention Deficit Hyperactivity Disorder (ADHD). Fibers integrity will be measured using magnetic Resonance Imaging Techniques.

Detailed Description

ADHD is a neurodevelopmental trouble characterized by attentional deficits, impulsivity and motor hyperactivity. Morphological neuroimaging studies in ADHD children have revealed cerebellar abnormalities, however data in adults regarding cerebellum alterations are scarce. In this study we will analyse the conectivity of the cerebellum of adults ADHD patients. We will use diffusion tensor imaging (DTI) technique, and morphological data will be compared with the neuropsychological status.

Study Timeline

• Study Start: 2008-02
• Primary Completion: 2008-02
• Study First Submitted: 2008-05-22
• Study First Submitted QC: 2008-05-22
• Study First Posted: 2008-05-28
• Study Completion: 2008-07
• Status Verified: 2009-06
• Last Update Submitted: 2009-06-22
• Last Update Posted: 2009-06-23

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 19

Inclusion Criteria

Patient with ADHD :

• Diagnosis of ADHD
• 18 - 35 years old

Healthy volunteer :

• 18 - 35 years old
• no ADHD diagnosed

Exclusion Criteria

• Associated neurological or psychiatric pathologies
• Pregnant woman
• MRI counter indication

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Fractional anisotropy coefficient if fronto-cerebello-frontal loops.	visite 1

Trial Locations

Locations (2)

Charles Perrens Hospital; 🇫🇷 Bordeaux, France

University Hospital Bordeaux; 🇫🇷 Bordeaux, France