Alterations of Fronto-Cerebello-Frontal Loops in Attention Deficit Hyperactivity Disorder (ADHD) : A Study Using Magnetic Resonance Imaging (MRI)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Attention Deficit Disorder With Hyperactivity
- Sponsor
- University Hospital, Bordeaux
- Enrollment
- 19
- Locations
- 2
- Primary Endpoint
- Fractional anisotropy coefficient if fronto-cerebello-frontal loops.
- Status
- Terminated
- Last Updated
- 16 years ago
Overview
Brief Summary
The aim of this study is to investigate the integrity of connectivity between the neocortex and the cerebellum in the Attention Deficit Hyperactivity Disorder (ADHD). Fibers integrity will be measured using magnetic Resonance Imaging Techniques.
Detailed Description
ADHD is a neurodevelopmental trouble characterized by attentional deficits, impulsivity and motor hyperactivity. Morphological neuroimaging studies in ADHD children have revealed cerebellar abnormalities, however data in adults regarding cerebellum alterations are scarce. In this study we will analyse the conectivity of the cerebellum of adults ADHD patients. We will use diffusion tensor imaging (DTI) technique, and morphological data will be compared with the neuropsychological status.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patient with ADHD :
- •Diagnosis of ADHD
- •18 - 35 years old
- •Healthy volunteer :
- •18 - 35 years old
- •no ADHD diagnosed
Exclusion Criteria
- •Associated neurological or psychiatric pathologies
- •Pregnant woman
- •MRI counter indication
Outcomes
Primary Outcomes
Fractional anisotropy coefficient if fronto-cerebello-frontal loops.
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