MedPath

Cerebellar Loops and Attention Deficit Hyperactivity Disorder (ADHD)

Not Applicable
Terminated
Conditions
Attention Deficit Disorder With Hyperactivity
Registration Number
NCT00684931
Lead Sponsor
University Hospital, Bordeaux
Brief Summary

The aim of this study is to investigate the integrity of connectivity between the neocortex and the cerebellum in the Attention Deficit Hyperactivity Disorder (ADHD). Fibers integrity will be measured using magnetic Resonance Imaging Techniques.

Detailed Description

ADHD is a neurodevelopmental trouble characterized by attentional deficits, impulsivity and motor hyperactivity. Morphological neuroimaging studies in ADHD children have revealed cerebellar abnormalities, however data in adults regarding cerebellum alterations are scarce. In this study we will analyse the conectivity of the cerebellum of adults ADHD patients. We will use diffusion tensor imaging (DTI) technique, and morphological data will be compared with the neuropsychological status.

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
19
Inclusion Criteria

Patient with ADHD :

  • Diagnosis of ADHD
  • 18 - 35 years old

Healthy volunteer :

  • 18 - 35 years old
  • no ADHD diagnosed
Exclusion Criteria
  • Associated neurological or psychiatric pathologies
  • Pregnant woman
  • MRI counter indication

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Fractional anisotropy coefficient if fronto-cerebello-frontal loops.visite 1
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (2)

Charles Perrens Hospital

🇫🇷

Bordeaux, France

University Hospital Bordeaux

🇫🇷

Bordeaux, France

Charles Perrens Hospital
🇫🇷Bordeaux, France

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.