Coagulation Profile in Patients Undergoing Coronary Angiography and Percutaneous Coronary Intervention
- Conditions
- SmokingChronic Coronary Insufficiency
- Registration Number
- NCT05336669
- Lead Sponsor
- Centre of Postgraduate Medical Education
- Brief Summary
The activated clotting time (ACT), global thrombosis test (GTT-3), platelet inhibition P2Y12 (VerifyNow) test and serum coagulation factors will be measured in patients undergoing coronary angiography (CA) and percutaneous coronary intervention (PCI).
- Detailed Description
The activated clotting time (ACT), global thrombosis test (GTT-3) and platelet inhibition P2Y12 (VerifyNow) test and serum coagulation factors will be measured in patients undergoing coronary angiography (CA) and percutaneous coronary intervention (PCI) - 20 smoking and 20 non-smoking.The measurements will take place: before coronary angiography (CA), 10 minutes after unfractionated heparin (HNF), 2h after CA, 6h after CA, 30 days after CA
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 40
- patients scheduled do CA >18 years old
- pregnancy
- previous treatment with P2Y12 inhibitors, novel oral anticoagulants (NOAC) or warfarin acenocoumarol in last 24 hours
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ACT change Baseline ACT , 10 minutes ACT, 2 hours ACT, 6 hours ACT, 30 days ACT Activated Clotting Time
GTT-3 change Baseline GTT-3, 10 minutes GTT-3, 2 hours GTT-3, 6 hours GTT-3, 30 days ACT Global Thrombosis Test
VerifyNow change Baseline VerifyNow, 10 minutes VerifyNow, 2 hours VerifyNow, 6 hours VerifyNow, 30 days ACT Platelet inhibition P2Y12 test
- Secondary Outcome Measures
Name Time Method