A clinical study to know the effect of injection of normal saline through epidural catheter on the level of spinal anaesthesia in patients undergoing lower limb surgeries.

Phase 4

Not yet recruiting

Conditions: Medical and Surgical,

Registration Number: CTRI/2023/09/057943

Lead Sponsor: M S Rmaiah medical college

Brief Summary: combined spinal epidural anesthesia is a regional anesthesia technique preferred for lower limb surgeries due to its rapid onset through the spinal component and post operative pain relive through epidural component while avoiding the disadvantages of both. epidural volume extension is a modification of combined spinal epidural anesthesia where in normal saline is injected into the epidural space immedietly after the intrathecal dose as a part of CSEA so the injected volume of fluid in the epidural space causes compression of the CSF resulting in cephalad spread of local anesthetic present in the subarachnoid space. So in the present study objective is to compare the onset and duration of sensory blockade , maximum level of sensory blockade achieved and onset and duration of motor blockade. And also to compare thr effect of hemodynamic changes like hypotension, bradycardia and other side effects like nausea, vomiting and shivering.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 100

Inclusion Criteria

all patients undergoing elective lower limb surgeries under combined spinal epidural anaesthesia who fit into american society of anaesthesiologists (ASA) physical status I and II.

Exclusion Criteria

american society of anaesthesiologist (ASA) physical status III and above patient refusal patients in whom CSEA is contraindicated patients having allergy to drugs used in the study.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
onset & duration of sensory blockade	levels will be tested every minute until highest level is achieved & every 10 mins there after until 2 segment regression is achieved
maximum level of sensory blockade achieved	levels will be tested every minute until highest level is achieved & every 10 mins there after until 2 segment regression is achieved
onset and duration of motor blockade	levels will be tested every minute until highest level is achieved & every 10 mins there after until 2 segment regression is achieved

Secondary Outcome Measures

Name	Time	Method
hypotension	bradycardia

Trial Locations

Locations (1): M S Ramaiah Medical College Hospital
🇮🇳
Bangalore, KARNATAKA, India
M S Ramaiah Medical College Hospital
🇮🇳Bangalore, KARNATAKA, India
Dr Kavana S
Principal investigator
8762913202
kavana17297@gmail.com