Excitatory/Inhibitory imbalance in autism spectrum disorder
Withdrawn
- Conditions
- ASDautism10012562
- Registration Number
- NL-OMON49625
- Lead Sponsor
- Radboud Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
18 years or older
Dutch speaking
Normal or corrected-to-normal vision
Willingness and ability to understand nature and content of the study
IQ > 70
An established clinical diagnosis of autism spectrum disorder according to the
DSM-5 criteria (patient group only)
Exclusion Criteria
History of brain surgery or epilepsy
History of neurological treatment
Any acute or chronic neurological disorders.
Pregnancy
Claustrophobia
MRI incompatibility (metal parts in upper body, implants, medical devices or
medicinal plasters)
There is presence of a diagnosis of psychosis or bipolar disorder (patient
group)
There is presence of any DSM-5 axis I or axis II psychiatric disorders (control
group)
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>ASD symptoms (continuous measures of repetitive behavior problems and abnormal<br /><br>sensory processing as measured with the Repetitive Behaviour Scale and the<br /><br>Short Sensory Profile) and the degree to which these symptoms are associated<br /><br>with MRI-based functional and neurochemical measures in the anterior cingulate<br /><br>cortex (ACC) and visual cortex (V1) will be investigated. </p><br>
- Secondary Outcome Measures
Name Time Method <p>N/A</p><br>