Phase I study of hepatic arterial infusion chemotherapy with Miriplatin and 5-fluorouracil(MiF) for advanced HCC
Phase 1
- Conditions
- Hepatocellular carcinoma
- Registration Number
- JPRN-UMIN000003302
- Lead Sponsor
- Division of Gastroenterology,Kurume University School of Medicine
- Brief Summary
CR/PR/SD/PD:1/5/3/1 OS 6 months:90% , 12 manths:48% MST:297 days Safety: no ploblem
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
Not provided
Exclusion Criteria
1.Previous chemothrapy or TAE 2.Previous operation or RFA or PEIT within 6 months. 3.Extrahepatic metastasis or lymph nodes metastasis. 4.Concurrent infections(without hepatitis virus) 5.Active double cancers 6.Medical history of severe hypersensitivity. 7.Pregnant,lacting women or women with suspected pregnancy. 8.Inappropriate patients for this study judged by physicians.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method complication
- Secondary Outcome Measures
Name Time Method response evaluation overall survival