A phase 1 trial of hepatic arterial infusion chemotherapy with high dose cisplatin and 5-fluorouracil for unresectable advanced and recurrent hepatocellular carcinoma
Phase 1
- Conditions
- hepatocelllar carcinoma
- Registration Number
- JPRN-UMIN000015101
- Lead Sponsor
- Keio University, School of medicine, Department of Surgery
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 18
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Active second primary malignancies. (2) Within 3 years after radical treatment of another cancer (3) With extrahepatic metastasis. (4) Patients with ascites possessed clinical meaning. (5) Hepatic Encephalopathy (6) Critical renal failure or hemodialysis (7) Contraindication of CDDP and 5-FU (8) Any patients are pregnant/ nursing (9) After administration of TS-1 (10) Auditory disorder (11) Patients with serious infection (12) Gastrointestinal ulcer or bleeding (13) Uncontrolled DM (14) Those judged to be not suitable by the attending physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method