Effects of Equal-volume Creatine Supplementation With Different Dosing Strategies on Body Composition and Muscle Performance in Young Healthy Adults
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- Power
研究概览
简要总结
The purpose is to compare the effects of bolus ingestion (5 grams) vs. intermittent ingestion (2 x 2.5 grams) of creatine supplementation vs. placebo for 21 days on measures of body composition (lean tissue mass-indicator of muscle mass, total body water) and muscle performance (i.e., power, strength, endurance).
详细描述
Creatine is a naturally occurring compound produced in the liver and brain. Creatine can also be found in food products such as red meat and seafood or through commercially available manufactured creatine products (i.e. creatine supplementation).
Evidence-based research shows that creatine supplementation improves measures of body composition and muscle performance. However, the optimal creatine supplementation protocol to achieve these benefits is unknown.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 39 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •if you are 18-39 years of age
- •if you have not been performing resistance training for at least 4 weeks prior to the start of the study.
排除标准
- •if you are pregnant or nursing
- •have taken creatine monohydrate within 30 days prior to the start of the study
- •if you have pre-existing allergies to the placebo (corn-starch maltodextrin)
研究组 & 干预措施
Placebo
(Servings 1: 8 grams of placebo in the morning; Serving 2: 8 grams of placebo in the evening) for 21 days.
干预措施: Placebo (Dietary Supplement)
Creatine Intermittent
(Serving 1: 2.5 grams of creatine monohydrate + 5.5 grams of placebo in the morning; Serving 2: 2.5 grams of creatine monohydrate + 5.5 grams of placebo in the evening) for 21 days.
干预措施: Creatine (Dietary Supplement)
Creatine Bolus
(Serving 1: 5 grams of creatine monohydrate + 3 grams of placebo in the morning; Serving 2: 8 grams of placebo in the evening) for 21 days.
干预措施: Creatine (Dietary Supplement)
结局指标
主要结局
Power
时间窗: baseline, day 21
Vertical Jump (cm)
Whole-body lean mass (kg)
时间窗: baseline, day 21
Bioelectrical impedance analysis
Strength
时间窗: baseline, day 21
1-repetition maximum leg press and chest press (kg)
Endurance
时间窗: baseline, day 21
Repetitions to fatigue for leg press and chest press (total number)
Hydration
时间窗: baseline, day 21
Total body water (kg) using bioelectrical impedance analysis
次要结局
未报告次要终点
研究者
Darren Candow
Professor
University of Regina