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Clinical Trials/ChiCTR-OCC-11001181
ChiCTR-OCC-11001181CompletedPhase 1

饮食诱导肥胖的胃肠激素研究

国家自然科学基金(30872108)1 site in 1 country60 target enrollmentStarted: April 1, 2010Last updated:
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Trial Snapshot

Phase
Phase 1
Status
Completed
Sponsor
Enrollment
60
Locations
1
Primary Endpoint
Ghrelin, CCK, GLP-1, insulin, glucose
Study OverviewStudy DesignEligibility CriteriaArms & InterventionsOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

观察改善咀嚼行为对能量摄入及胃肠激素的作用

Study Design

Study Type
观察性研究
Primary Purpose
病例对照研究
Masking
受试者 是

Eligibility Criteria

Ages
20 to 25 (—)
Sex
Male

Inclusion Criteria

  • •1、BMI ≥ 18.5 and ≤ 23 kg/m2 为正常体重，BMI ≥ 27.5 kg/m2 为肥胖；2、无任何口腔疾病；3、体重稳定；4、身体健康；5、不在服用任何处方药。

Exclusion Criteria

  • •1、患有牙齿或口腔疾病，咀嚼功能不正常者；2、正在减肥者；3、对某些食物过敏者。

Arms & Interventions

正常 1

每口食物咀嚼 15 次

正常 2

每口食物咀嚼 40 次

肥胖 1

每口食物咀嚼 15 次

肥胖 2

每口食物咀嚼 40 次

Outcomes

Primary Outcomes

Ghrelin, CCK, GLP-1, insulin, glucose

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
国家自然科学基金(30872108)

Study Sites (1)

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