Pharmacogenetic and Antidepressant Treatment in Elderly
- Conditions
- Depression
- Registration Number
- NCT02856477
- Lead Sponsor
- Centre Hospitalier Universitaire de Besancon
- Brief Summary
The study aims to assess the therapeutic benefits of the adaptation of the antidepressant dose to the metabolic capacity (cytochrome P450 2D6) of elderly depressed patients.
Therapeutic benefits are evaluated through the enhancement of efficiency, decrease of the action time and the after effects.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 28
- current major depressive disorder
- antidepressant treatment
- dextromethorphan contra-indication
- other psychiatric disorder
- kidney failure
- liver failure mini mental State Examination (MMSE)<18
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method patient remission 6 months remission is defined by a Montgomery and asberg depression rating (MADRS) score\<10.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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Trial Locations
- Locations (1)
CHU Besancon
🇫🇷Besancon, Doubs, France
CHU Besancon🇫🇷Besancon, Doubs, France