Clinical Profile of Hyponatremia (Low Sodium Levels) in Stroke patients in a Tertiary Care Hospital
- Conditions
- Health Condition 1: G46- Vascular syndromes of brain in cerebrovascular diseases
- Registration Number
- CTRI/2021/06/034043
- Lead Sponsor
- Dr Shubha Seshadri
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
1. Patients more than 18 years of age
2. Based on history, clinical examination, and radiological findings ( either CT Scan or MRI),
diagnosed as acute stroke
3. Presenting within 48 hours of stroke onset
4. Who have not received any anti-cerebral edema measures (like diuretics, steroids, mannitol)
before presenting to the hospital
5. Patientâ??s fulfilling all of the above criteria will be screened on the basis of routine electrolyte
samples sent; and those with hyponatremia ( serum Na+ < 135 mg/dl) will be further evaluated
for its cause.
1. Patients with recurrent stroke or residual paralysis
2. Patients with a h/o head trauma
3. Patients with any co-existing infection, e.g.- bacterial pneumonia, pulmonary TB, or evidence
of CNS infection â?? meningitis, encephalitis
4. Patients with renal failure or chronic kidney disease (CKD)
5. Patients with liver failure or chronic liver disease
6. Patients with congestive cardiac failure (CCF)
7. Patients with any malignancy et- bronchogenic cancer, leukemia, lymphoma or brain
tumours
8. Patients with a h/o any surgery within the last 3 months
9 Patients with a h/o gastroenteritis and diarrhea
10. Patients taking any drugs that cause hyponatremia eg- Diuretics, Carbamazepine, Fluoxetine
1. Patients with recurrent stroke or residual paralysis
2. Patients with a h/o head trauma
3. Patients with any co-existing infection, e.g.- bacterial pneumonia, pulmonary TB, or evidence
of CNS infection â?? meningitis, encephalitis
4. Patients with renal failure or chronic kidney disease (CKD)
5. Patients with liver failure or chronic liver disease
6. Patients with congestive cardiac failure (CCF)
7. Patients with any malignancy et- bronchogenic cancer, leukemia, lymphoma or brain
tumours
8. Patients with a h/o any surgery within the last 3 months
9 Patients with a h/o gastroenteritis and diarrhoea
10. Patients taking any drugs that cause hyponatremia eg- Diuretics, Carbamazepine, Fluoxetine
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence and severity of hyponatremia in patients of ischemic stroke and haemorrhagic <br/ ><br>stroke will be calculated and tabulatedTimepoint: End of study period of 2 years
- Secondary Outcome Measures
Name Time Method To determine the etiology of hyponatremia in stroke patients and classify them <br/ ><br>according to the type of stroke (Ischemic/Haemorrhagic) and (anterior/posterior <br/ ><br>circulation)Timepoint: End of study period of 2 years;To find out the severity of hyponatremia in strokes and itâ??s relation to the diseaseTimepoint: End of study period of 2 years