Effect of Use of Hypotension Prediction System in Prevention of Postoperative Acute Kidney Injury in Radical Cystectomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Acute kidney injury
研究概览
简要总结
It is a single-center randomized controlled trial that aims to figure out the effect of the hypotension prediction index (HPI) on the prevention of acute kidney injury (AKI) after radical cystectomy. The primary hypothesis is that HPI software guidance prevents postoperative AKI by reducing the duration and severity of intraoperative hypotension (IOH).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing radical cystectomy with neobladder reconstruction
- •Patients undergoing radical cystectomy with ileal conduit urinary diversion
排除标准
- •Unable to voluntarily give consent
- •Unable to use both radial arteries due to such reasons: prior surgery on the radial artery, breast cancer history with axillary LN dissection, AV fistula for renal replacement therapy, or abnormal Allen's test.
研究组 & 干预措施
HPI group
Managing intraoperative hemodynamic condition under the HPI guidance
干预措施: BP management with HPI guidance (Device)
Standard care group
Managing intraoperative hemodynamic condition with standard anesthesia care (blinding the HPI monitor screen)
结局指标
主要结局
Acute kidney injury
时间窗: Seven day after the operation
Occurrence of acute kidney injury after radical cystectomy
次要结局
- Hypotension prediction index(From applying HPI (hypotension prediction index) monitor to the arterial line to the end of the anesthesia)
- Depth and duration of hypotension(From applying HPI (hypotension prediction index) monitor to the arterial line to the end of the anesthesia)
研究者
Sooyoung Cho
Assistant Professor
Ewha Womans University Mokdong Hospital