Vitamin D3 Supplementation On Level Of Blood Glucose Among Vitamin D Deficient Adult With Prediabetes.

Phase 4

Not yet recruiting

• Conditions: Vitamin D deficient Adult with prediabetes

• Registration Number: CTRI/2014/12/005290
• Lead Sponsor: A Rathiga

Brief Summary

A randomized controlled trail proposed to conduct on to assess the effect of vitamin d3 supplementaion on level of blood glucose among vitamin D deficient adult with prediabetes among 288 samples in selected teritary hospital, kanchhepuram. The primary outcome of the study will be selected subject will maintain the vitamin d level 50 or above 50 ng/dl and blood glucose level 80 to 100 mg/dl as per the who criteria.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2014-12-14
• Study Start: 2015-01-19

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 288

Inclusion Criteria

• Subject who belongs to age 30 years up to 60 years individuals who met the diabetes risk score criteria both male and female fasting plasma glucose level 110 to 125 mg/dl Oral glucose tolerance test 140 to 199mg/dl.
• vitamin D3 below 30ng/dl.

Exclusion Criteria

• Subjects who with diabetes under medication currently using vitamin D supplements hypercalcaemia above 2.65mmol/l liver disease, Virus or autoimmune hepatitis and cirrhosis history of hyperparathyroidism history of arthritis history of Pulmonary Tuberculosis history of malabsorption Pregnant women History of chronic renal failure, nephrotic syndrome, Renal stone hypothyroidism, and HIV patients on antiviral drugs.
• History of malignant diseases History of inflammatory diseases.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
25 hydroxy vitamin d3 reach 50 or above 50 ng/dl	Oral supplementation of vitamin D3(Cholecalciferol) 60,000IU/week for 8 weeks followed by 60,000IU/month for 2months to achieve the serum vitamin D 50ng/dl and post test evaluation will be done on 16 th week
Blood glucose level 80 to 100 mg/dl	Oral supplementation of vitamin D3(Cholecalciferol) 60,000IU/week for 8 weeks followed by 60,000IU/month for 2months to achieve the serum vitamin D 50ng/dl and post test evaluation will be done on 16 th week

Secondary Outcome Measures

Name	Time	Method
Vitamin d 3 supplementation Effect on Insulin resistance and	Effect on triglyceride

Trial Locations

Locations (1)

Medical OPD and Master health checkup department in chettinad Hospital and research Institute; 🇮🇳 Kancheepuram, TAMIL NADU, India

Medical OPD and Master health checkup department in chettinad Hospital and research Institute

🇮🇳Kancheepuram, TAMIL NADU, India

A Rathiga

Principal investigator

09791025299

dhiya.rathiga@gmail.com