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Efficacy of timolol in arresting progression in Keratoconus

Not Applicable
Conditions
Health Condition 1: null- Keratoconus
Registration Number
CTRI/2017/09/009859
Lead Sponsor
I
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
120
Inclusion Criteria

Patients between 15 to 30 years of age with a definitive diagnosis of keratoconus as in accordance with guidelines of Collaborative Longitudinal Evaluation of Keratoconus Group

Exclusion Criteria

Patients with associated ocular surface disease

Systemic disorders like bronchial asthma cardiovascular disorders

Pre existing glaucoma or use of antiglaucoma drugs

H/o prior treatment with collagen cross linking

H/o prior corneal hydrops

History of use of contact lens in the last 3 weeks

Pregnancy or lactation during the period of the study

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Corneal tomographyTimepoint: Baseline (Day 0), Month 3, and Month 6.
Secondary Outcome Measures
NameTimeMethod
Best spectacle-corrected Visual Acuity (BSCVA)Timepoint: Baseline (Day 0), Month 3, and Month 6.;Fundus and optic nerve head evaluationTimepoint: Baseline (Day 0), Month 3, and Month 6.;Intraocular pressureTimepoint: Baseline (Day 0), Month 3, and Month 6.;Manifest refractionTimepoint: Baseline (Day 0), Month 3, and Month 6.;Slit lamp biomicroscopyTimepoint: Baseline (Day 0), Month 3, and Month 6.;Uncorrected Visual Acuity (UCVA)Timepoint: Baseline (Day 0), Month 3, and Month 6.
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