Serial Measurement of a Plasma Stroke Biomarker Panel in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass
Completed
- Conditions
- Cardiac Surgery
- Registration Number
- NCT00812656
- Lead Sponsor
- Klinikum Ludwigshafen
- Brief Summary
The purpose of this study is to investigate changes in new plasma stroke biomarker panel in patients undergoing cardiac surgery with the use of cardiopulmonary bypass.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- Age > 18 years
- Elective cardiac surgery with the use of cardiopulmonary bypass
Exclusion Criteria
- Patients undergoing emergent procedures
- Patients with preoperative mechanical support
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in stroke index day before surgery; first and second day postoperatively
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways do plasma stroke biomarkers in NCT00812656 correlate with during cardiopulmonary bypass?
How do biomarkers like S100B and NSE compare to novel panels in predicting postoperative stroke after cardiac surgery?
Which biomarker levels in NCT00812656 identify high-risk patients for cerebral ischemia during bypass procedures?
What adverse neurological events are associated with cardiopulmonary bypass in NCT00812656 and how are they managed?
Are neuroprotective agents or anti-inflammatory therapies being evaluated alongside biomarker monitoring in cardiac surgery trials?
Trial Locations
- Locations (1)
Klinikum Ludwigshafen
🇩🇪Ludwigshafen, RLP, Germany
Klinikum Ludwigshafen🇩🇪Ludwigshafen, RLP, Germany