A RANDOMISED TWO ARM ACTIVE CONTROLLED CLINICAL STUDY OF GASTRO ESOPHAGEAL REFLUX DISEASE (MARZ-E-INEKAS-E-HUMUZAT-E-MEDA WO MARI ) WITH COMPOUND UNANI FORMULATION JAWARISH-E-TABASHEER AND RABEPRAZOLE
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- to evaluate the clinical efficacy of jawarish e tabasheer in cases of GERD
研究概览
简要总结
GERD (Gastroesophageal Reflux Disease):
GERD is a chronic condition where stomach acid frequently flows back into the esophagus, causing irritation and inflammation. This occurs due to weakness or relaxation of the lower esophageal sphincter (LES).
Key Symptoms are :-Heartburn (burning chest pain), Regurgitation of food or sour fluid, Bloating, belching, Difficulty swallowing, Chronic cough or sore throat
Jawarish-e-Tabasheer is a classical Unani formulation traditionally used for strengthening the digestive system and reducing excess heat and bile (Safra).
Since the chronic use of PPIs in the management of GERD cause hypomagnesemia,osteoporosis ;the efficacy of unani drug JAWARISH E TABASHEER is evaluated
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient of either sex Age : 20-60 years.
- •Patient with following complains :Regurgitation, Heart burn, Epigastric Pain,Nausea ,Indigestion,Flatulence,Loss of appetite, Water brash, Heaviness in abdomen after meals.
排除标准
- •Pregnant and lactating women Psychiatric patients Uncontrolled diabetes GERD due to LOS causes .
- •Patients with cardiac, respiratory, liver and renal dysfunction.
- •Patients with: Bleeding disorders Known peptic ulcers Gastric carcinoma Hiatus hernia Crohn’s disease Zollinger Ellison Syndrome Esophageal strictures, stenosis Other malignancies.
结局指标
主要结局
to evaluate the clinical efficacy of jawarish e tabasheer in cases of GERD
时间窗: once in 2-4 weeks
次要结局
- To prevent from complications of GERD like peptic strictures, Barret’s esophagus, esophageal adenocarcinoma.(Once in Two weeks)
研究者
Dr Amreen
Government Nizamia Tibbi College and Hospital