The effect of Alprostadil on improvement of acute asthma attack
Phase 2
- Conditions
- Asthma.Mixed asthma
- Registration Number
- IRCT2016052828129N1
- Lead Sponsor
- Vice chancellor for research, Ahwaz Judishapur University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 28
Inclusion Criteria
age range of 18 to 65 years; proved diagnosis of asthma based on primary outcomes (wheezing, cough, and breathlessness triad).
Exclusion criteria: pulmonary diseases similar to asthma (such as interstitial lung disease)? having proven coagulation disorders and being treated with anticoagulants? history of chronic bronchitis; having acute medical disorders, cardiac, coronary vascular and arrhythmia diseases? being pregnant; treating with beta agonist nebulizers during last 6 hours, using cigarette more than 10 packs in year.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Forced expiratory volume in 1 second. Timepoint: Before intervention and in 20, 40, and 60 minutes after intervention. Method of measurement: Researcher-made questionnaire.;Peak expiratory flow rate. Timepoint: Before intervention and in 20, 40, and 60 minutes after intervention. Method of measurement: Researcher-made questionnaire.;Clinical symptoms severity. Timepoint: Before intervention and 40 minutes after intervention. Method of measurement: Researcher-made questionnaire.
- Secondary Outcome Measures
Name Time Method Respiratory rate. Timepoint: Before intervention and 40 minutes after intervention. Method of measurement: Researcher-made questionnaire.;Pulse rate. Timepoint: Before intervention and 40 minutes after intervention. Method of measurement: Researcher-made questionnaire.;Blood pressure rate. Timepoint: Before intervention and 40 minutes after intervention. Method of measurement: Researcher-made questionnaire.;Atrial oxygen saturation. Timepoint: Before intervention and 40 minutes after intervention. Method of measurement: Researcher-made questionnaire.;Level of consciousness. Timepoint: Before intervention and 40 minutes after intervention. Method of measurement: Researcher-made questionnaire.;Wheezing. Timepoint: Before intervention and 40 minutes after intervention. Method of measurement: Borg dyspnea scale.;Using respiratory peripheral muscles. Timepoint: Before intervention and 40 minutes after intervention. Method of measurement: Borg dyspnea scale.