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临床试验/NCT01516385
NCT01516385Unknown不适用

Detection of Peripheral Blood Biomarkers in Intermediate Phase Spinal Cord Injury: Correlation With Neurological and Functional Outcomes, and Comparison to Other Central and Peripheral Neurological Conditions.

Sheba Medical Center1 个研究点 分布在 1 个国家目标入组 150 人开始时间: 2012年1月最近更新:
适应症

试验速览

阶段
不适用
入组人数
150
试验地点
1

研究概览

简要总结

This research looks for markers in the blood of people with spinal cord injury that may be a sign of injury severity, or serve as a clue to the degree of recovery. Investigators would also like to compare the marker profile of these patient with that of other neurological conditions such as stroke and Guillain-Barre syndrome.

Patients participating in this trial will be those accepted to neuro-rehabilitation in Sheba medical center, Israel. They will join the trial at their arrival to the ward, no less than 2 week after the beginning of their condition, but no later than 3 months.

Patients will be examined by the research staff three times:

  1. At arrival, the patients will be neurologically examined and their functional abilities will be assessed. Blood will be drawn and sent to the lab.
  2. At 6 months after the beginning of the neurological condition the same will be repeated: the patients will be neurologically examined and their functional abilities will be assessed, and blood will be drawn and sent to the lab.
  3. The final examination will take place 1 year after the beginning of the neurological condition. This time only the neurological and functional abilities will be assessed without blood tests.

The blood samples will be tested in the research lab. Then investigators shall compare the clinical findings with the laboratory findings, and see if any of the markers found reflect the injury severity or predict the recovery.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis of traumatic or non-traumatic Spinal cord injury, Guillain-barre syndrome or Stroke
  • No more than 3 months after injury or disease onset
  • Condition severe enough to necessitate hospital/day care unit
  • Signed the informed consent form

排除标准

  • Psychiatric or cognitive situations that may interfere with the trial

研究者

申办方类型
Other Gov
责任方
Sponsor

研究点 (1)

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