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Dissolving Effects of Cicer Arietinum on Renal and ureteral Stones

Phase 2
Conditions
Calculus of kidney and ureter.
Calculus of kidney and ureter
Registration Number
IRCT2017042433623N1
Lead Sponsor
School of Iranian Traditional Medicine. Iran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
70
Inclusion Criteria

Inclusion Criteria: Renal or ureteral stone diagnosis with size between 6 to 10 millimeter by urologist in any composition and using sonography, K.U.B and/or C.T scan(without contrast); Age between 18 to 50 in both genders; Patient should not be affected by any grade of hydronephrosis; Anatomical position of stones in renal pelvis, calyxes, upper-middle-lower portion of ureter; Controllable pain, nausea and vomiting by oral NSAIDS and oral anti emetics; Intending to participation in study, inform consent and signing it's written form before recruiting in the study; Not consumption any chemical or herbal drug at least one month before entering the study; Not consumption the nephrolithogen drugs; Normal range of renal function tests(BUN, Cr); Normal range of liver function tests(SGPT, SGOT, Alk Phos); Absence any symptom and sign of urinary tract infection.
Exclusion criteria: Patients with renal or ureteral stone/s less than 5 mm or more than 11 mm in size; Affecting by urinary stone complications(any grade of hydronephrosis and U.T.I); Patients who need to surgery, other procedures or emergency interventions; Uncontrolled pain, nausea and vomiting despite using oral NSAIDS and oral anti emetics; Consumption other types of chemical or herbal drugs except those prescribed in this study; Subjects intending to withdraw at any time during the course of study; Having a history of significant problems(diabetes mellitus, renal dysfunctions, hepatic dysfunctions and peptic ulcer); Pregnancy; Lactating.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in size of stone/s. Timepoint: before intervention and just after termination of intervention. Method of measurement: in millimeter by using ruler (visual).
Secondary Outcome Measures
NameTimeMethod
Change in plasma concentration of BUN ? Creatinine ? ALT? AST. Timepoint: before intervention and just after termination of intervention. Method of measurement: mg/dl for BUN and Creatinine , u/lit for AST and ALT.
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