Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

Not yet recruiting

• Conditions: Hypertension; Intracerebral Hemorrhage; Stroke
• Interventions: Drug: Clevidipine Injection; Drug: Alternate IV Antihypertensive Regimen

• Registration Number: NCT06402968
• Lead Sponsor: Zeenat Qureshi Stroke Institute

Brief Summary

The aim is to compare the rate of hypertensive subjects with ICH who reach SBP target with stability within 60 minutes of enrollment, among patients treated with IV clevidipine with those treated with alternate IV antihypertensive regimen.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-05
• Study First Submitted: 2024-05-02
• Study First Submitted QC: 2024-05-02
• Last Update Submitted: 2024-05-02
• Study First Posted: 2024-05-07
• Last Update Posted: 2024-05-07
• Study Start: 2024-06-01
• Primary Completion: 2026-05-30
• Study Completion: 2026-05-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
designated clevidipine hospitals	Clevidipine Injection	-
designated non-clevidipine hospitals	Alternate IV Antihypertensive Regimen	-

Primary Outcome Measures

Name	Time	Method
Blood Pressure Monitoring	15 minutes	To compare the rate of hypertensive subjects with ICH who reach SBP target with stability within 60 minutes of enrollment, among patients treated with IV clevidipine with those treated with alternate IV antihypertensive regimen. SBP target with stability is defined as achieving a SBP of less than 150 mm Hg and greater than 130 mm Hg with two subsequent consecutive recordings at least 15 minutes apart that show SBP of less than 150 mm Hg and greater than 130 mm Hg.