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临床试验/EUCTR2009-018016-25-NL
EUCTR2009-018016-25-NL进行中(未招募)1 期

Dopamine-serotonin dysbalance in patients with dystonia

Academic Medical Center0 个研究点开始时间: 2010年2月1日最近更新:
适应症
相关药物

试验速览

阶段
1 期
状态
进行中(未招募)
发起方

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
All

入选标准

  • Age 35 years or older
  • Primary focal dystonia diagnosed and treated with botulinetoxin injections in the Academic Medical Center
  • Informed consent
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range

排除标准

  • Other forms of dystonia
  • SSRI use in the past 6 months prior to or during the study
  • Use of other anti-depressants during the study, especially MAO-B inhibitors
  • Symptomatic therapy for dystonia other than botulinetoxin, e.g. baclofen or other muscle relaxants.
  • Use of medication with a known effect on dopamine or serotonin receptors or transporters or with a known interaction with Escitalopram (e.g. L-DOPA, dopamine-agonists, ritalin, NSAID’s, aspirin, tryptophan, carbamazepine, etcetera)
  • Pregnancy or nursing

研究者

发起方
Academic Medical Center

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