NCT00753558已完成不适用
A Randomized,Double-Blind,Placebo-Controled Trial of Selective Digestive Decontamination Using Oral Gentamicin and Oral Polymyxin E for Eradication of Carbapenem-Resistant Klebsiella Pneumoniae Carriage
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 试验地点
- 2
- 主要终点
- Eradication of CRKP carriage measured by negative rectal swabs
研究概览
简要总结
There is an urgent need to control our current national outbreak of carbapenem-resistant Klebsiella pneumoniae (CRKP). The purpose of this study is to eradicate CRKP gastrointestinal carriage using selective digestive decontamination (SDD); with buccal and oral gentamicin and polymyxin E administration. This will reduce infections and hopefully mortality caused by CRKP.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hospitalized men and women with a positive rectal swab for CRKP
- •Age 18 years or older
排除标准
- •Age less than 18 years
- •Pregnant women, lactating women
- •A known allergy to the study drugs
结局指标
主要结局
Eradication of CRKP carriage measured by negative rectal swabs
时间窗: Two days after treatment ends
次要结局
- No new in-hospital acquisition of CRKP(Six weeks)
研究者
研究点 (2)
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